Expert Advice from Bonitas Medical Fund
Bonitas – innovation, life stages and quality care

The lowdown on diabetes in children and teenagers

The diagnosis of type 1 diabetes in children can be overwhelming, especially in the beginning. Suddenly you and your child – depending on your child’s age – must learn how to count carbohydrates and monitor blood sugar levels and give injections. But even though there is no cure, it can be managed.  Diabetes is a chronic disease, characterised by high levels of blood glucose. ‘In type 1 diabetes your immune system, the body’s system for fighting infection, attacks and destroys the insulin-producing cells of the pancreas,’ explains Dr Themba Hadebe, Clinical Executive at Bonitas Medical Fund. ‘It can lead to serious damage to the heart, blood vessels, eyes, kidneys and nerves. However, advances in blood sugar monitoring and the delivery of insulin have improved blood sugar management and quality of life for children with type 1 diabetes.’ Statistics currently show that there are close to 5 000 adolescents that live with Type 1 diabetes in South Africa. Type 1 diabetes can be either: Hyperglycaemia: When your blood sugar levels are too high. It is the hallmark of diabetes onset and it usually continues to occur on and off after you start treatment Hypoglycaemia: Sugar levels are too low. This usually occurs as the result of diabetes treatment, particularly insulin administration which lowers blood sugar How does diabetes in children and adolescents start? It can come on suddenly or gradually in children and teens and parents often aren’t aware of the symptoms or patterns that point to a potential diabetes diagnosis. Symptoms may be similar to those of flu but, if diabetes is the cause, the sooner it’s diagnosed, the better. Symptoms of Hyperglycaemia: High blood sugar Increased hunger The body’s cells are not able to utilise glucose for energy due to a lack of insulin or insulin resistance, leading to a craving for more food. Dry mouth: A dry mouth is one of the most common symptoms which can cause trouble chewing, swallowing or speaking, dry cracked lips, sores or infections in the mouth or a furry, dry tongue Frequent urination (especially at night):  Excess glucose in the blood spills into the urine, drawing water with it and increasing the frequency of urination. This in turn increases thirst Weight loss:  Despite increased food intake, the body starts breaking down fat and muscle for energy, due to the lack of insulin Fatigue: The body’s cells cannot use glucose for energy efficiently, leading to feelings of tiredness and fatigue Blurry vision: High sugar levels in the blood can damage the tiny blood vessels in the eyes, causing fluid to seep into the lens, potentially causing blurry vision Slow-healing sores or frequent infections:  Over time, high blood sugar levels narrow your blood vessels, slowing blood circulation and restricting much needed nutrients and oxygen from getting to the wounds. As a result, even small cuts and wounds may take weeks or months to heal Fruity-smelling breath: The breakdown of fat for energy produces ketones, which can cause a fruity smell in the breath Ketoacidosis: This is when blood sugar levels are very high and the body starts making ketones. It is a very serious condition that needs immediate in hospital treatment, sometimes in the intensive care unit. If not treated right away, there is a  risk for diabetic coma. A child with a diabetic coma loses consciousness because of brain swelling due to very high blood sugar levels Symptoms of Hypoglycaemia: Low blood sugar  Trembling: Low blood sugar levels trigger the release of adrenaline, which causes shakiness Sweating:  The body’s response to low blood sugar includes releasing adrenaline, which can cause sweating Hunger: The brain detects low blood sugar and signals the body to eat Irritability or moodiness: Low blood sugar levels can affect brain function, leading to mood changes Fatigue: The brain and muscles are deprived of glucose, leading to feelings of tiredness Paleness: The body’s stress response to low blood sugar can cause blood vessels to constrict, leading to paleness Headaches: The brain is sensitive to changes in blood sugar levels, low levels can cause headaches How is type 1 diabetes treated? A daily dose of insulin is needed to keep the blood glucose level within normal ranges. Insulin is given either by injection or via an insulin pump. Your child’s healthcare provider will show you how to give your child insulin with either method.  Dr Hadebe says, ‘to make it easier for children and adolescents to monitor glucose levels and administer insulin the Scheme offers Insulin Pump Therapy and Continuous Glucose Infusion Monitoring device (CGM) to members under the age of 18.’ Eating the right foods to manage blood glucose levels. This includes timing meals and counting carbohydrates Exercise Regular blood testing Regular urine testing for ketone levels How can I help my child live with type 1 diabetes? The diagnosis affects the entire family emotionally – there are various support groups and organisations for children with Type 1 diabetes and their families. A younger child may not understand all the life changes, such as glucose monitoring and insulin injections, this can lead to anxiety and depression. They may feel different from their peers, try to treat them as a normal child, with managing diabetes as just one aspect of their daily life. Ask your healthcare provider for more information and call them if you need help.  Also ensure they are following the treatment plan and are eating the right foods, exercising and testing their blood and urine.  Early detection and comprehensive management are key to ensuring children with Type 1 diabetes lead healthy, fulfilling lives. Remember that your GP is your first port of call for all your healthcare needs. 

Bonitas – innovation, life stages and quality care

Pregnancy, your body and your baby – week 30 of your pregnancy

You now officially have ten weeks left of your pregnancy, this can be both an exciting and overwhelming realisation, and feelings of anxiety during this time are normal. Your little one’s kicks and growing baby bump are reminders that your due date is increasingly getting closer. Your body at week 30 Your back and feet may be increasingly getting more painful as your baby grows in size. Swollen ankles and feet are normal, so remember to give yourself some time to put your feet up and invest in some comfortable footwear. Bloating, constipation and  stretch marks are normal at this point in your pregnancy. The fatigue you felt in your first trimester may be returning. You could be struggling to sleep at night, which will leave you feeling drained during the day. Don’t be afraid to ask for help at this time, you’ll need extra hands now and after your baby has been born. Your baby at week 30 As your delivery date grows closer, your baby is constantly growing in size, and at this point she is roughly the size of a cabbage. Your little one is also prepping for the big day and they should have (or will be soon) changed position, facing head down with their face towards your back (known as the occipito-anterior position) – ready to enter the pelvis. This is the ideal position for birth, however it is possible for your baby to be lying another way inside you. Some babies will only turn this way closer to your due date. Things to keep in mind at week 30 It’s normal to feel anxious about your approaching delivery. Going to antenatal or birth classes can help you feel more prepared for what is to come. Do exercises that can help you prepare your body for what it will go though, certain yoga and pilates positions can strengthen your muscles and help make the process quicker and smoother. If you find that your anxiety is overwhelming, chat to a health professional, as you may be experiencing antenatal anxiety. This is nothing to be ashamed about, and is something that can be managed with the help of professionals.

Bonitas – innovation, life stages and quality care

Pregnancy, your body and your baby – week 29 of your pregnancy

Week 29 of your pregnancy and you may notice that your body is taking more strain. Be mindful of this and don’t be afraid to take it easy if needed. Make sure that you’re still eating healthily (and remembering to take your prenatal vitamins) and exercising gently, both are important to your health as well as your growing baby’s. Your body at week 29 You are now entering the last phase of your pregnancy, and because of this you may find this very challenging, both physically and mentally.  Your back, pelvis and feet are probably aching, and you’ll experience constipation, frequent urination and shortness of breath. Your baby at week 29 Your baby is now filling more of your womb, this means that any kicks, which used to be soft and barely notable, may feel more like hard pokes now. Your little one is also growing rapidly, and will probably have doubled in weight before birth. At this point many of their organs are almost fully developed, meaning they have a good chance of survival if born premature. That being said, their lungs still have lots of developing to do, which is why preemies need help breathing via a ventilator. Things to remember If you haven’t already, start planning your maternity leave. In South Africa, moms are entitled to four months of unpaid leave. If you’re still feeling able to work, you’ll probably want to keep most of your leave for after birth, so that you can spend as much time with your growing baby as possible. Generally speaking, maternity leave begins about a month before birth –  and the good news is dads are now entitled to 10 consecutive days of parental leave. Your employer is obliged to keep your job for you until you return from leave, so you won’t have to worry about losing your job.

Bonitas – innovation, life stages and quality care

Pregnancy, your body and your baby – week 28 of your pregnancy

Welcome to week 28 of your pregnancy, you are now in your third trimester – the final stretch before birth! Your baby will do lots of growing during this time, and your body may start taking some strain in the final weeks before delivery. You’ll probably be feeling both nervous and excited, soon you’ll be able to take your little one home! How your body will be feeling at week 28 If you haven’t started experiencing it already, you may notice that back ache and pelvic pain are becoming an issue. This is due to the fact that pregnancy hormones cause your ligaments to loosen, which can cause lower back and pelvic pain. Your changing centre of gravity also puts strain on your back. Excruciating pain in your pelvic reason is cause for concern and the culprit could be symphysis pubis dysfunction (SPD). Luckily this isn’t harmful to your baby, but is probably very painful to you. Chat to your doctor if you’re feeling pain that you see as abnormal. They’ll probably recommend a physiotherapist to you as physio can help minimise your pain and improve your muscle function. Other common week 28 pregnancy symptoms include Braxton-Hicks contractions, frequent urination, swollen ankles and feet, sleeping problems, stretch marks, heartburn and indigestion and constipation. Your baby at week 28 Your little one is growing fast, and is now the size of a head of lettuce. Around this time your baby will begin to open and close their eyes,  and can sense changes in light. Your baby’s heart rate will have lowered to about 140 bpm (and at birth this will have dropped to around 130 bpm). If you were to have an ultrasound now you may notice hair on your baby – this is known as lanugo, which is fine hair that grows on babies before birth. This will disappear at birth or shortly afterwards.

Bonitas – innovation, life stages and quality care

Pregnancy, your body and your baby – week 27 of your pregnancy

Congratulations, you are now in the last week of your second trimester and approaching the third, which will start at the beginning of week 28 –  so you are nearing the final stretch of your pregnancy. You’ll find that you’re probably becoming more used to your little one moving around inside of you and while you may have enjoyed less fatigue during trimester two, this unfortunately may begin to change. Your baby at week 27 Your baby is starting to pack on the final pounds before birth (which should be in 13 weeks, but not all babies arrive at their due date). Inside of your uterus, your little one will be kicking and grasping, slowly developing their muscle tone before birth. Your baby will also be practicing breathing and swallowing with the amniotic fluid. Your body at week 27 Haemorrhoids are a common pregnancy, thanks to your uterus becoming larger and putting pressure on your veins. Haemorrhoids are swollen veins in the anus and rectum, and these are both uncomfortable and painful. While these are unwanted, they generally aren’t harmful to you or your growing baby and normally go away after birth. Other pregnancy symptoms common during this time are leg cramps, aching pelvis and back, heartburn bleeding gums,  constipation, trouble sleeping, frequent urination and stretch marks. Things to remember at week 27 At week 27, something you can start considering is putting together a birth plan. A birth plan is a written document that communicates your wishes during your pregnancy (think of the ideal way you’d like your birth to go) as when the time comes, you probably won’t be thinking clearly.  There is no right or wrong way to go about doing this – some may be detailed and others just cover the basics, the choice is yours!

Bonitas – innovation, life stages and quality care

Pregnancy, your body and your baby – week 26 of your pregnancy

Although you are yet to meet your baby, they are slowly taking over your life and you may notice weekly and even daily changes in your body. Some days you’ll feel better than others, and it’s important that you take each day as it comes. Both by taking advantage of your good days, and being gentle on yourself on the bad ones. How your body may feel during this time Tiredness, an achy body, a sore mouth and stretch marks are all part of your pregnancy journey. Your belly and breasts are also growing, so make sure that you accommodate your body and dress in clothes that are both supportive and comfy. Your baby’s growth at week 26 Your little one’s lungs are now working hard, getting ready for the day that she’ll need to start using them. At this time the lungs start to produce surfactant, which’ll make it possible for your baby to breathe at birth. Your baby’s suck reflex is  growing stronger (they may even suck their thumb!), and their eyes may open for the first time around now and they’ll start to practice blinking. Not only this, but your little one also has eyelashes that are starting to grow. Now that your baby can hear you, you can also spend some time talking to them. Research has shown that babies prefer the sound of their mothers voices and you may even notice that they start responding to the sound of your voice, and by late pregnancy they should be able to distinguish between voices. What you should keep in mind at this time Something to keep aware of during your pregnancy is the possibility for gestational diabetes. Gestational diabetes is high blood sugar levels during pregnancy, and it’ll go away after birth. However, moms who develop gestational diabetes are at higher risk of developing type 2 diabetes after birth. Warning signs are unusual thirst, frequent urination and dizziness, if you feel like you are checking these boxes then it’s important to speak to your doctor about treatment. If treated effectively, there is no reason you shouldn’t have a healthy pregnancy.

Advice from the experts
CRYOSAVE

Keeping Your Little One Safe: Essential Burn Prevention Tips for New Parents

Every parent worry about their child’s safety, and the kitchen can be a minefield of potential hazards – especially for curious little ones. Burns are a common concern, with thousands of scalding incidents happening every year. But fear not, new parents! By following a few simple precautions, you can create a safe and enjoyable cooking environment for you and your budding chef. Pippie’s Story: A Powerful Reminder Pippie Kruger’s story is a stark reminder of the importance of burn prevention. This brave South African child suffered severe burns at a young age. Thankfully, advancements in medical care, like stem cell therapy, helped Pippie through the recovery process, allowing for successful skin grafting. While medical technology offers incredible support, prevention is always the best medicine. Tips for a Safe Home: Kitchen Safety Zone: As mentioned earlier, the kitchen can be a hotspot for burns. Implement the “No Child Zone” concept, keeping your child in a safe play area while you cook. Utilize back burners, turn pot handles inward, and keep hot food and drinks out of reach. Beyond the Kitchen: Burns can happen anywhere. Secure fireplaces and space heaters with sturdy barriers. Keep electrical cords out of sight and away from curious hands. Teach your child about the dangers of outlets and never allow them to play with electrical appliances. Sun Safety: Sunburns are a form of burn, and even on cloudy days, UV rays can damage your child’s delicate skin. Apply sunscreen with SPF 30 or higher liberally and reapply often, especially after swimming or sweating. Hot Water Woes: Scalding is a serious threat. Adjust your water heater to a safe temperature, ideally 48°C (120°F) or as recommended by the manufacturer. Install scald-resistant faucets in the bathtub and sinks your child uses. Chemical Concerns: Household cleaners and chemicals can cause burns. Keep them securely stored in high cabinets or locked away, out of reach of inquisitive youngsters. Remember: In case of a burn, immediately cool the affected area under cool running water for 10-15 minutes. For serious burns, call emergency services (10111 in South Africa) for immediate medical attention. By following these simple tips and fostering a safety-conscious environment, you can ensure your kitchen becomes a place of happy memories, not unfortunate accidents. Let us all work together to keep our precious little ones safe from burns!

Bonitas – innovation, life stages and quality care

Pregnancy, your body and your baby – week 17 of your pregnancy

Week 17 your baby is getting bigger, and this week they’ll start developing more fatty tissue. You may have started to notice an achy back and pelvis, and getting a good night’s sleep may have become increasingly more difficult. Your body at week 17 At week 17 you may see an increase in your appetite, a far cry from the nausea you experienced in your first trimester. Your breasts are also increasing in size as they prepare for milk production – for some women this growth is more than others. Your growing baby’s weight can also put added strain onto your spine and pelvis, meaning you could start to experience backache. Prenatal yoga and supportive chairs and shoes, are all ways in which you can help your body feel more comfy. Your baby at week 17 Your baby is now the size of an onion or orange, and at this time her fatty tissue is starting to form – this will help keep her warm after she’s born. Although the head is still the biggest part of the body, the body proportions are starting to become more even as your pregnancy progresses. Your baby is now learning to suck, so that when they’re born they can easily feed, although this reflex won’t mature until later in your pregnancy. Around this time, your baby’s finger prints will also form. Things to remember at week 17 Your pregnancy changes your whole life, including the way you sleep. Even though the position you sleep in is something fairly simple, which you probably hadn’t put much thought into before. As your pregnancy progresses, a good night’s sleep is something that may become increasingly difficult. It’s recommended that you avoid sleeping on your back in your second and third trimester, as your uterus and baby can put pressure on your spine and vena cava. Sleeping on your left side is ideal as this supports optimal circulation. Once your belly gets bigger, you can even look into getting a pregnancy pillow, which offers support for your entire body.

CRYOSAVE

Transforming Treatment: Stem Cell Molecules Target Inflammation and Immune Dysfunction

In the rapidly evolving field of medical science, stem cells have emerged as a beacon of hope for treating various diseases. This article delves into the multifaceted role of stem cells in combating viral diseases and managing autoimmune disorders like Multiple Sclerosis (MS). It explores how certain types of stem cells can not only mitigate viral replication but also modulate the immune response, shifting it from a state of inflammation to repair. The article further discusses the potential of umbilical cord stem cells in regulating the immune system, providing new insights into the treatment of MS. Read on to discover the transformative potential of stem cells in medical therapeutics. The Role of Stem Cells in Immune Response Some stem cell types release molecules that reduce viral replication and decrease the cytokine storm and inflammation induced by the immune system. These stem cells are part of both the innate and adaptive immune systems. Stem Cells in Post-Viral Recovery An important aspect of stem cells’ ability to alleviate viral diseases, especially post-clearance complications, is their capacity to shift the innate and adaptive immune systems from an inflammatory state to a repair state. This makes the molecules released from certain efficacious and safe stem cell types a potential new avenue for therapeutic development in Covid-19, particularly for late-stage inflammation and tissue damage once the virus has cleared, especially in the aged population. Stem Cells and Multiple Sclerosis (MS) The Problem: Immune System Abnormalities in MS MS is characterized by immune system attacks against myelin, despite the disease’s cause still being unknown. T-cells, which are immune system cells, enter the brains of MS patients and react with the myelin sheath that surrounds and shields neurons. The unregulated activity of T-cells, which leads to their unusual hostility, is often mediated by T regulatory cells (Tregs). The Solution: Mesenchymal Stem Cells (MSCs) MSCs, which are immature cells that can become any type of cell in the body, are one potential means of restoring T-cell control. Bone marrow contains a type of stem cell called MSCs. It has been demonstrated that MSCs activate Tregs, which in turn regulates T-cell activity. The Experiment: Umbilical Cord Stem Cells (UC-MSCs) Human umbilical cord contains MSC-equivalent stem cells, or UC-MSCs. Compared to MSCs, these cells are more stable, cause fewer immunological reactions, and have a greater capacity for expansion. Researchers cultured UC-MSCs in combination with immune system cells found in the blood of both healthy individuals and MS patients to investigate if these cells may regulate the immune system in MS. Unused human umbilical cords, which provide a plentiful and noninvasive source of these cells, and blood cells from ten healthy donors (mean age 28.38) and twelve RRMS patients (mean age 53.75) were used to create UC-MSCs. The Results: UC-MSCs and Tregs Researchers found that when UC-MSCs were present, resting T-cells from MS patients had a notably higher proportion of Tregs. Additionally, UC-MSCs were able to reinstate the regulatory function of Tregs, by inducing the synthesis of certain proteins known as cytokines that regulate T-cell activity. Overall, these findings showed that using umbilical cord stem cells to treat multiple sclerosis can successfully lower aberrant immune system activity. The potential of stem cells in treating viral diseases and autoimmune disorders like Multiple Sclerosis (MS) is immense. Their ability to modulate the immune system, reduce inflammation, and promote repair presents a promising avenue for future therapeutic development. Particularly, the use of umbilical cord stem cells offers a stable, non-invasive, and effective approach to control aberrant immune system activity. As we continue to unravel the mysteries of stem cells, we move closer to a future where diseases may be managed more effectively and efficiently, heralding a new era in medical therapeutics. References: Cuascut, F. and Hutton, G. (2019) ‘Stem cell-based therapies for multiple sclerosis: Current perspectives’, Biomedicines, 7(2), p. 26. doi:10.3390/biomedicines7020026. Forraz, N. and McGuckin, C.P. (2011) ‘The umbilical cord: A rich and ethical stem cell source to advance regenerative medicine’, Cell Proliferation, 44(s1), pp. 60–69. doi:10.1111/j.1365-2184.2010.00729.x. Khandelwal, V. et al. (2022) ‘Stem cell therapy: A novel approach against emerging and re-emerging viral infections with special reference to SARS-COV-2’, Molecular Biology Reports, 50(3), pp. 2663–2683. doi:10.1007/s11033-022-07957-2. Mebarki, M., Abadie, C., Larghero, J. et al. Human umbilical cord-derived mesenchymal stem/stromal cells: a promising candidate for the development of advanced therapy medicinal products. Stem Cell Res Ther 12, 152 (2021). https://doi.org/10.1186/s13287-021-02222-y Rowden, A. (2021) Stem cell therapy for multiple sclerosis: Explanation and safety, Medical News Today. Edited by N. Hammond. Available at: https://www.medicalnewstoday.com/articles/stem-cell-multiple-sclerosis Sleem, A. and Saleh, F. (2020) ‘Mesenchymal stem cells in the fight against viruses: Face to face with the invisible enemy’, Current Research in Translational Medicine, 68(3), pp. 105–110. doi:10.1016/j.retram.2020.04.003.

Parenting Hub

Bronchostop Introduces New Cough Syrup, Bronchostop Nite

We’ve all been there, tossing and turning at 2 a.m., disturbed by a relentless cough. Whether it’s your partner’s persistent hacking or your child’s distressing cough fits, a night-time cough doesn’t just steal sleep; it robs us of our peace of mind and the energy needed to face the day. Recognising this, iNova Pharmaceuticals announces the launch of a new addition to their Bronchostop range; Bronchostop Nite, which relieves a dry cough as well as a night-time cough, early symptoms of common cold and low grade fever1. A night-time cough is most often dry and persistent and can be caused by a variety of factors including the common cold, the flu, allergies, and exposure to environmental irritants2. A night-time cough can be disruptive and extremely frustrating. A recent study showed that a cough is one of the most common causes of night-time awakenings in colds and flu patients. A cough can have a significant impact on quality of life; affecting the ability to work, sleep and function during the day. Having a good night’s sleep helps the body recover faster3. Bronchostop Nite contains a unique combination of natural ingredients, Marshmallow root dry extract, Ribwort Plantain leaf dry extract and Lime flower dry extract. These ingredients work together to reduce the urge to cough and help you to get a better night’s sleep1,4. The Marshmallow root dry extract and Ribwort Plantain leaf dry extract have a thick, gel like consistency which creates a soothing, protective coating on the throat to relieve local irritation and soothe inflammation1,6. Excess mucus from the nasal passages can drip down the throat (post-nasal drip) to irritate the throat lining and trigger the cough reflex2. Mouth breathing at night can cause further dehydration and irritation of the throat lining which can increase cough receptor sensitivity and as a result increased coughing7,8. Bronchostop Nite’s ingredients have humectant properties which help restore hydration and reduce the urge to cough1,6. The last ingredient in Bronchostop Nite is Lime flower dry extract, which has a mild diaphoretic effect, which helps promote sweating to relieve mild feverish colds. The natural ingredients in Bronchostop Nite helps ensure a peaceful night’s sleep1,5. According to renowned medical research group the Mayo Clinic, rest is one of the most important ways your body fights off infections. Ironically, getting enough rest can also be the hardest thing to accomplish when a patient has a nagging night-time cough9. Fortunately, Bronchostop Nite is now available in leading pharmacies countrywide. Bronchostop Nite is suitable for the whole family from 4 years old. It is available in a strawberry flavour1 and can be purchased at Clicks, Dis-Chem and all leading independent pharmacies countrywide. Click here to buy now. Learn more about Bronchostop Nite or rest of the Bronchostop range at www.bronchostop.co.za. Should your coughing persist please consult your healthcare professional.       References:   Bronchostop® Nite professional information, May 2023. Healthline – What’s Causing My Unproductive Dry Cough at Night and How Can I Treat It (2019). Phillipson, G; Aspley, S; Fietze, I. Perceptions of the Importance of Sleep in Common Cold—Two Online Questionnaire-Based Surveys. SN Comprehensive Clinical Medicine (2020) 2:596–605. April 2020. IQVIA. IMS TPM February 2024 Assessment Report on TiliaCordata. Doc ID: EMA/HMPC/337067/2011 Murgia V et al. Upper Respiratory Tract Infection-Associated Acute Cough and the Urge to Cough: New Insights for Clinical Practice. Pediatr Allergy Immunol Pulmonol. March 2020; Sinus and Snoring Specialists – Mouth Breathing can cause a bad nights sleep (2020) at https://www.sinussnoringent.com/blog/snoring/mouth-breathing/mouth-breathing-could-be-causing-your-snoring/#(website accessed on 14 March 2024) NHS – Why do I still have a cough? (2021) at https://mft.nhs.uk/app/uploads/2021/05/Cough.pdf. Everyday Health. Why Your Cough Symptoms Get Worse at Night (2023) at https://www.everydayhealth.com/hs/cold-and-flu-relief/nighttime-cough/ (website accessed on 14 March 2024). Scheduling Status: S0 Proprietary name (and dosage form): Bronchostop® Nite Syrup. Composition: Each 5 ml oral solution contains: 62.5 mg Marshmallow root dry extract, 45.5 mg Lime flower dry extract and 50.0 mg Ribwort plantain leaf dry extract. Pharmacological Classification: Complementary medicine: Discipline Specific Traditional Claims D33.7 Combination product. These unregistered medicines have not been evaluated by the SAHPRA for their quality, safety or intended use. For more information speak to your health care professional. Further information is available on request from iNova Pharmaceuticals. Name and business address of applicant: iNova Pharmaceuticals (Pty) Limited. Co. Reg. No. 1952/001640/07, 15e Riley Road, Bedfordview. Tel. No. 011 087 0000. www.inovapharma.co.za. IN4791/24.

Parenting Hub

SURVIVING BABY’S FIRST COLD AND FLU SEASON – A Parent’s Guide

Ah, the joys of welcoming a new bundle of joy into your life! As any seasoned parent will tell you, along with the adorable coos and cuddles come some not-so-adorable worries, especially when you’re gearing up for your baby’s first cold and flu season. While we can’t put your little one in a bubble (though, honestly, who wouldn’t want to?), we can arm you with some tips and tricks to help you both survive and thrive during those chilly months. So, let’s dive into this survival guide for Baby’s First Cold and Flu Season!  Understanding the Risks  First, let’s talk about why your baby is more susceptible to germs. Newborns, especially those under six months, come into this world with an immune system that’s still learning the ropes. That makes them prime targets for those pesky cold and flu bugs. But don’t worry; we’ve got your back!   Symptoms in Babies  Your baby won’t be able to tell you they’re feeling under the weather, so, you’ll have to rely on other signs like a fever, runny or stuffy nose, sneezing, coughing, congestion, crankiness, and changes in their eating habits or sleep schedule.1a   While most baby colds and flu cases are like a minor speed bump (colds typically only last seven to 10 days),1b some viruses can turn into the Grand Canyon of problems, escalating into more serious illnesses.1c The key is to keep a watchful eye and act fast if things start to get dicey.  Preventative Measures  Now that you’re up to speed on the symptoms, let’s move on to how you can play superhero in your baby’s defence against germs.   Vaccinations: Superheroes need their trusty sidekicks, and for your baby, that means vaccinations. Keep your baby up-to-date with those recommended shots to reduce the risk of nasty viruses.2a  Limit Exposure: Keep your baby away from germs as much as possible – and that means avoiding people who are sick. If friends or family are feeling a bit off, kindly ask them to postpone their visit until they’re feeling better.2b  Hand Hygiene: The power of clean hands is immense! Make sure everyone in your household practices good hand hygiene, especially before handling your little one, preparing their meals or feeding them.2c  Regular Cleaning: It’s time to clean house! Disinfect touched surfaces like doorknobs, light switches, and baby’s toys. Opt for baby-friendly, non-toxic cleaning products – no toxic chemicals allowed in this hero’s headquarters!2d  Breastfeeding: If you can swing it, breastfeeding is like giving your baby a superhero cape. Breast milk is packed with antibodies that can help your baby ward off infections.3 If you’re on Team Formula, make sure you’re sterilising those bottles and gear properly. Always follow the manufacturer’s instructions for formula preparation and storage.  Baby’s Sleeping Position: This one’s non-negotiable, folks. Always put your baby to sleep on their back – and this applies to both day napping and night-time sleeping.4a Lots of research from all over the world shows that putting your baby to sleep on their back at the beginning of each nap or bedtime, day or night, really cuts down the risk of sudden infant death syndrome (SIDS).4b Consider having a crib or bassinet in your room for the first few months so that you can keep an eye on your little bundle of joy.  Avoid Smoking: Smoking is a big villain in this story. Inhaling second-hand and third-hand smoke poses serious risks, particularly for babies. Passive exposure to smoke significantly heightens the chances of tots facing respiratory infections and other nasties. It can mess with their breathing, heart rate, and growth, making them more susceptible to sudden unexpected death in infancy (SUDI).5a Babies exposed to second-hand smoke are more likely to have a laundry list of health issues, including asthma, bronchiolitis, bronchitis, childhood cancers (yikes!), croup, ear infections, meningococcal disease (think meningitis and septicaemia), pneumonia and tonsillitis.5b Plus, those chemicals from second-hand and third-hand smoke can mess with a child’s developing brain, and trust us, baby brains are like sponges!5c Kids who already have lung or health problems are at an even higher risk from this smoke shindig.5d Oh, and one last thing – if babies live in a smoking household, their chances of picking up the smoking habit as teens double.5e That’s not cool because it can mess with their adult health too. So, keep the lair smoke-free!  How Panado® – The Ultimate Chill-Beating Pain Fighter – Can Help  Panado® is trusted6 by South African families to offer relief of pain and fever associated with headaches, toothache and colds and flu.  The range for adults is conveniently available in tablet, capsule or effervescent form to suit individual preferences. The effervescent format is innovative and ready to work immediately.6 & 7  For kids and babies, parents trust8 Panado® to be gentle on little tummies9 but tough on pain and fever this, winter. The paediatric range includes peppermint flavoured syrup in convenient 5 ml sachets, strawberry flavoured syrup, peppermint flavoured alcohol and sugar-free syrup, recently launched grape flavoured colourant-free, tartrazine-free, alcohol-free, and sugar-free syrup and peppermint flavoured infant drops with a dosage dropper.  Always administer using a medicine measure or a syringe. Do not exceed the recommended dose.  Dosage details can be found at https://panado.co.za/dosage-calculator/ and are calculated according to your child’s age and weight.  Final Words  While it might feel like you’re fighting an epic battle, remember that you’ve got the tools and knowledge to be the superhero your baby needs. Every baby is unique, and your parental instincts are your trusty sidekick. If you ever feel uncertain or worried about your baby’s health, don’t hesitate to seek guidance from your paediatrician. With a healthy, hygienic environment, a little immune system boost, some good old-fashioned parenting love and the power of Panado®, you’ll sail through your baby’s first winter season with flying colours. Stay strong, superhero parents! Embrace the Winter Warrior within with the Adcock Ingram Range, featuring Panado®, Cepacol®, Compral®, and ViralGuard™, available from Pick n Pay, Checkers including Hypers, Shoprite, Clicks,

Bonitas – innovation, life stages and quality care

Pregnancy, your body and your baby – week 16 of your pregnancy

You are now 4 months pregnant, and have 24 weeks left to go before you birth day, although this may seem far away your baby has done so much growing in these past 16 weeks and still has lots left to do before they are born.   Your body at 16 weeks Your pregnancy hormones can make your veins stretch, giving you varicose veins. While these distinctive purple lumps are the prettiest sight, generally they are painless and harmless. Pregnancy brain is another sign of a baby that you may have noticed, many moms-to-be notice they may become more forgetful or inattentive. The exact reason for this isn’t clear, however, stress and having many items on your to-do list could be contributing factors towards this. You may also notice some pregnancy weight gain (which is normal and nothing to worry about!) and your boobs will have probably gone up a few cup sizes as your body preps for breastfeeding. Be sure to invest in comfortable bras, such as maternity or sports bras, as this can help ease any discomfort. Your baby at 16 weeks Your baby is now the size of an avocado. This week may be the one that you first start to notice small kicks from your little on moving around. Another exciting marker of this time is the fact that your baby can start hearing your voice, so make sure you chat to them throughout your day. This’ll also be roughly the time that their eyes become more sensitive to light, their bones and muscles are hardening and strengthening and their eyebrows, hair and lashes are forming.  Things to take note of around this time. During pregnancy you may struggle with constipation. This is a fairly common pregnancy complaint thanks to pregnancy hormones and the extra iron you’re taking in your prenatal vitamins. Eating more fibre, drinking lots of water, and exercise can help keep you regular.  If you’re still struggling, chat to your doctor and they may prescribe stool softeners to help.

Parenting Hub

New on the shelves! Panado® Grape Flavoured Paediatric Syrup

Panado®’s new paracetamol-based Grape flavoured1 paediatric syrup is colourant-free, tartrazine-free, alcohol-free, and sugar-free. It provides soothing relief of pain and fever in little ones.  Parents trust2 Panado® to be gentle on tummies3 and to provide comfort to babies and kids. Always administer using a medicine measure or a syringe. Do not exceed the recommended dose. Dosage details can be found at https://panado.co.za/dosage-calculator/ and are calculated according to your child’s age and weight. Approx.. RSP for 100ml – R69.95 and 50ml R38.95. Panado® products are available from Baby City, Pick n Pay, Checkers including Hypers, Shoprite, Clicks, Dis-Chem and independent pharmacies. For more information, visit https://panado.co.za/ and join the conversations on Facebook.     2023032710267635 References:   Panado ® Paediatric Alcohol Free – Grape Flavour. Approved package insert. October 2022. Circana, MT,  November 2023 MAT. Bannwarth B. Gastrointestinal safety of paracetamol: is there any cause for concern? Expert Opin Drug Saf. 2004 Jul;3(4):269-72. doi: 10.1517/14740338.3.4.269. PMID: 15268644. Available from: https://pubmed.ncbi.nlm.nih.gov/15268644/#. Last accessed February 2023.  

Bonitas – innovation, life stages and quality care

Measles – it’s a serious illness

The World Health Organization (WHO) has warned of an ‘alarming’ increase in measles cases – almost 45-fold in Europe last year – but outbreaks of new cases and even deaths are being reported globally. WHO believe this is a result of fewer children being vaccinated against the disease, especially during the Covid pandemic. However, measles is preventable, thanks to a vaccine that was introduced in 1963. Since 2000, the measles vaccination programme has averted an estimated 57 million deaths worldwide.  However, the Covid-19 pandemic disrupted global vaccination activities which, in 2021, resulted in the lowest measles-containing-vaccine first-dose (MCV1) coverage levels since 2008. Dr Themba Hadebe, Clinical Executive at Bonitas Medical Fund takes a look at this ‘childhood’ disease to remind us about what causes it, the symptoms and why we should vaccinate. What is measles? Measles is caused by a virus and can affect anyone but is most common in children.  It infects the respiratory tract and then spreads throughout the body. Some of the more common measles symptoms include: High fever  Cough Runny nose  Red, watery eyes (conjunctivitis)   A rash all over the body (3-5 days after symptoms begin). Complications of measles can lead to: Ear infections Diarrhoea Pneumonia (infection of the lungs) Other respiratory infections Encephalitis (inflammation of the brain) which occurs in about one in every 1 000 people with Measles. Blindness Measles can be serious Measles is so much more than just a fever and rash that clears up in a few days.  It can cause serious health complications, especially in children under the age of 5 and adults over the age of 30. If a woman catches Measles during pregnancy, it can be dangerous for the mother and can result in her baby being born prematurely with a low birth weight. Even with the best care, people can still die after contracting measles (1 to 3 out of 1 000 people). Being vaccinated is the best way to prevent getting sick with measles or spreading it to other people. Measles is contagious Measles is easily spread through the air when an infected person coughs or sneezes. It is very contagious: One person can infect up to 9 out of 10 people around them if they are not adequately protected. In fact, an infected person can spread measles to others even before they know they have the disease – from up to four days before developing the measles rash to around four days afterwards. The measles vaccine The best protection against measles is the Measles-Mumps-Rubella (German Measles) (MMR) vaccine. The MMR vaccine provides long-lasting protection against all strains of measles. Your child will need two doses of MMR vaccine for best protection: The first dose at between 12 and 15 months of age The second dose at between 4 through 6 years The Measles-Mumps-Rubella-Varicella (MMRV) vaccine, which protects against four diseases, is also available to children from 12 months through 12 years of age. Treating measles As measles is caused by a virus, there’s no specific medical treatment, it has to run its course.  However, if your child has measles they need to drink plenty of liquids, get lots of rest and stay at home to prevent spreading the infection. Measles outbreaks The people most at risk during a measles outbreak are non-immune person (not vaccinated or vaccinated but did not develop immunity). Unvaccinated young children and pregnant persons are at highest risk of severe measles complications. The fact is that measles is still common and with a break in the vaccination regime we are seeing more outbreaks.  The best way to fight it and prevent it spreading is to vaccinate. Did you know? South Africa follows International Guidelines in providing vaccines to children. This programme is known as the Expanded Programme of Immunisation (EPI). Parents need to take responsibility to ensure their child is vaccinated on time: Not only to help protect the child against certain illnesses but also to contribute to the overall health of children in the general population.  ‘Childhood vaccines are a critical part of a child’s health, they work by stimulating and teaching the immune system how to fight certain infections,’ explains Dr Hadebe. ‘Bonitas recognises this and we cover immunisation, on most plans, according to EPI up to the age of 12.’

CRYOSAVE

Preterm Birth Awareness: Supporting Healthier Beginnings

A full-term pregnancy is best for your baby’s health. Full-term pregnancies usually last approximately 40 weeks. Preterm birth is defined as one where a baby is born too early before 37 weeks of pregnancy have been completed. Babies who are born early may suffer from long-term health issues that could include e.g. cerebral palsy, mental retardation, visual and hearing impairments, and general poor health and growth problems. In 2021, preterm births were recorded in approximately 1 of every 10 infants born in the United States. The preterm birth rate rose 4% in 2021, from 10.1% in 2020 to 10.5% in 2021. Causes of premature birth There are factors that may increase the risk of premature birth, such as an infection or placental problems, but the exact causes remain unknown. Some risk factors for preterm birth include being pregnant with multiple babies, clinical uterus or cervix problems (whether current or historical), tobacco or substance abuse, and closely spaced pregnancies (less than 18 months). However, most premature births occur with a natural frequency and doctors have little idea as to the reason why. Is it possible for preterm labor to stop by its own accord? For about 3 in 10 women, preterm labour stops on its own. If it doesn’t stop, then medication or treatment may be given to try delaying the birth. Current data suggest that in the United States, the preterm birth rate has increased to more than 10.5%.  This rate is higher than in any other developed country where this rate compares to 7.4% in England and Wales, 6% in France, and 5.8% in Sweden. There is a general global increase in the rate of preterm births. What are the signs of preterm birth? Mild cramps (period cramps), pressure in the belly or pelvis, low and dull backache, contractions where the muscles in the belly tighten every 10 minutes or less, vaginal spotting or bleeding, changes in vaginal discharge, water breaks. We cannot always prevent preterm birth’s. However, you can lower the risk by following this advice. See your doctor early and regularly in your pregnancy for prenatal care. Take care of any health problems, including diabetes, high blood pressure, or depression. Don’t smoke, drink, or use illegal drugs. Eat a diet that includes a variety of healthy foods especially foods rich in iron and folic acid. Gain a healthy amount of weight (not too much or too little). Protect yourself from infections (wash your hands well; don’t eat raw meat, fish, or unpasteurized cheese; use condoms when having sex; limit domestic pet chores such as changing cat litter). Reduce stress in your life, try yoga, meditation, being active, joining support groups. Be active every day. Try to get 30 minutes of exercise daily South Africa has experienced an increase in early delivery of baby’s post COVID-19. This is confirmed by a preterm birth rate of 11%. CryoSave South Africa urges mothers-to-be to take good care of yourself and your baby during pregnancy. If you are determined to bank your baby’s cord blood to ensure future stem cell health insurance possibilities, talk to your healthcare provider early in your pregnancy. This will enable you to prepare and review your stem cell storage options. Preterm babies need extra oxygen and help from machines to help them breathe which can damage their lungs. A life-saving treatment using stem cell from the umbilical cord should soon be available. References https://www.youtube.com/watch?v=itZI3uHs_28 https://health-e.org.za/2020/11/18/premature-births-antenatal-access/ https://www.marchofdimes.org/about/news/march-dimes-2022-report-card-shows-us-preterm-birth-rate-hits-15-year-high-rates

Bonitas – innovation, life stages and quality care

Pregnancy, your body and your baby – week 15 of your pregnancy

Congratulations, you and your baby are now at week 15, while your baby still has lots of growing to do, you should make sure that you make the most out of feeling more energetic during trimester two. Join prenatal classes, enjoy walks outside and start planning how you’ll rearrange your house for the arrival of your new bundle of joy. Your baby at week 15  Your little one is now roughly the size of an apple or pear, and at this point your baby’s ears and eyes are starting to become more developed, and are moving into the correct place on their head. Soon they may even be able to hear the sound of your voice. During this time their bones and muscles are also getting stronger, not only this but her limbs are getting longer and are able to move. You won’t be able to feel any movement just yet, but it won’t be long! Your body at week 15 At week 15, your increased energy levels may also mean that you may experience increased libido. Although you may have higher energy levels, you’ll probably also notice that your expanding belly is itchy, thanks to stretching skin. If you are feeling increasingly hungry, thanks to a reduction in morning sickness, be aware of what you’re putting into your body. Certain foods, such as ripened cheese, can be damaging to your baby. However, the inclusion of healthy snacks can be beneficial to both of you, and by doing research or chatting to a dietician, you can make sure that you include food groups that’ll be nutritious to you and your baby. Things to keep in mind at week 15 Another pregnancy symptom is sensitive gums and teeth. The reason for this is hormonal changes which increase the blood flow to your gums, making them swell. Not only this but you may be more susceptible to gum disease and pregnancy gingivitis (which about half of all women experience during pregnancy). Because of this it’s important that you look after your teeth and gums, and check in the dentist during your pregnancy.

Parenting Hub

Panado® Launches Grape-Tastic New Flavour To The Paediatric Range

Panado® has expanded their paediatric range with a new Grape flavour syrup,1 designed to help relieve pain and fever in children1. As a trusted2 name in South Africa, Panado® knows that parents want convenient and great tasting products for their children. That’s why our new grape flavour is colourant-free, tartrazine-free, alcohol-free, and sugar-free1. Providing comfort to little ones who are feeling unwell can be a daunting task for parents, particularly when children are not able to successfully communicate their discomfort. Panado®  is trusted2 by South African families for providing relief of pain and fever1 in babies, toddlers, and children, but it is also convenient and great tasting. This makes it a go-to choice for parents who want a reliable solution that is easy to administer and appealing for their little ones to take. With Panado® Paediatric Syrup – Grape Flavour, you can easily give your little one pain and fever relief. Fever is one of the most frequently cited reasons parents or caregivers seek medical help for their children. It is often a source of concern for parents and health care practitioners, who believe it may be linked to a greater risk of seizures (fits).3a A fever is defined as a body temperature of more than 38° C in children.3b Our syrup contains paracetamol, a good option for treating pain and fever in children,4 and caters to diverse tastes and preferences while being gentle on little tummies5. We know that getting children to take medicine can be a challenge, which is why we’ve made sure that our grape flavour is also taste-bud friendly and easy to take. With its clear syrup, there’s no need to worry about messy clothes or unsightly stains. Plus, the grape flavour is sure to make medicine time more appealing for kids. Dosage details for the Panado® range of products can be found at https://panado.co.za/dosage-calculator/ and are calculated according to your child’s age and weight. Add in your child’s age and weight, and our calculator will automatically calculate how much paracetamol you should give your child, and which product is best suited for your child. So, next time you find yourself in the middle of a parenting rollercoaster with pain and fever, remember to reach for Panado® Paediatric Syrup – Grape Flavour – the clear choice for parents and kids alike! Parents trust2 Panado® for the power to fight their little one’s pain and provide fast6 relief when needed most.  Panado® products are available at Baby City, Pick n Pay, Checkers, including Hypers, Shoprite, Clicks, Dis-Chem, and Independent Pharmacies. For more information, visit visit https://panado.co.za/ and join the conversations on Facebook. 2023032710267635   References:   Panado ® Paediatric Alcohol Free – Grape Flavour. Approved package insert. October 2022. Circana, MT,  November 2023 MAT. InformedHealth.org [Internet]. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2006-. Fever in children: Overview. 2013 Dec 18 [Updated 2019 Jun 6].Available from: https://www.ncbi.nlm.nih.gov/books/NBK279455/. Last accessed February 2023. de Martino M, Chiarugi A. Recent Advances in Pediatric Use of Oral Paracetamol in Fever and Pain Management. Pain Ther. 2015 Dec;4(2):149-68. doi: 10.1007/s40122-015-0040-z. Epub 2015 Oct 30. PMID: 26518691; PMCID: PMC4676765. Available from: https://pubmed.ncbi.nlm.nih.gov/26518691/. Last accessed February 2023. Bannwarth B. Gastrointestinal safety of paracetamol: is there any cause for concern? Expert Opin Drug Saf. 2004 Jul;3(4):269-72. doi: 10.1517/14740338.3.4.269. PMID: 15268644. Available from: https://pubmed.ncbi.nlm.nih.gov/15268644/#. Last accessed February 2023. Wilcock A, Twycross R. Therapeutic reviews: Acetaminophen (Paracetamol). Journal of Pain and Symptom Management, 2013;46(5):747-755.

CRYOSAVE

How cord blood stem cells save lives

Throughout the world the most widely used stem cell treatment is hematopoietic (or blood) stem cell transplantation, for example, bone marrow transplantation. However, in recent years, cord blood stem cell transplants have shown superior results in comparison to bone marrow, in terms of risks of rejection, contamination, and infection. They also surpass bone marrow in their capability to restore cells damaged or deceased from chemotherapy or radiation treatments. Cord blood has a lower risk of graft-vs-host disease (GVHD). Approximately 1.24 million blood cancer cases occur yearly worldwide, accounting for roughly 6% of all cancer cases. Worldwide, almost every 4 minutes someone is diagnosed with a blood cancer and every 9 minutes, someone dies from a blood cancer. It is estimated that every year, about 18,000 people, aged between 0 – 74 years of age, might benefit from a potentially life-saving bone marrow or umbilical cord blood transplant. Worldwide there are currently about 50,000 stem cell transplants done yearly, with growth at a rate of 10-15% per year. In the past 4 decades the recognition of stem cell treatments has drastically increased, mostly due to its high efficacy and recorded success rates of up to 80%. It is estimated that 1 in 3 people might one day benefit from regenerative cell therapy. Cord blood stem cells save lives. There are currently over 80 diseases approved for routine treatment with cord blood stem cells. In transplants cord blood stem cells helps rebuild a healthy blood and immune system that has been damaged by disease. There are some of the more than 80 diseases where a child could use his or her own cord blood. However, many of the diseases on the proven treatment list are inherited genetic diseases. Usually, a child with a genetic disease who is in need of a transplant would require a cord blood unit from a sibling or an unrelated donor. In this instance when a family has banked cord blood stem cells the matched sibling’s stem cells will be immediately available. Research indicates that transplants using cord blood from a family member are about twice as effective as transplants using cord blood from a non-relative. Cord blood and cord tissue stem cells are being studied in regenerative medicine clinical trials for conditions that have no remedy. Families that invest in cord blood, cord tissue, and placental tissue banking are not just investing in the medicine of today—they have realised the potential of stem cell and regenerative medicine in the future. The healing potential of hematopoietic stem cells (HSCs) as found in cord blood is a long way from being exhausted. There are promising trials underway (over 1300 stem cell trials currently) with these cells that have the ability to continue the innovation in treatment that started with the first successful stem cell transplants many years ago. These include stem cell treatments for some bone, skin and corneal (eye) injuries. These diseases can be treated by grafting or implanting tissues, and the therapy relies on stem cells within this implanted tissue. Some of these procedures are widely accepted as safe and effective by the medical community and are routinely used for treatment. However, various other diseases and applications of stem cells are yet to be proven in clinical trials and should be considered highly experimental. These unapproved treatments would benefit people that have autism, cerebral palsy, spinal cord injuries, type 1 diabetes, Parkinson’s disease, amyotrophic lateral sclerosis, Alzheimer’s disease, heart disease, stroke, burns, autoimmune diseases, cancer and osteoarthritis. Parents endeavour to keep their children and family safe, especially when dreaded disease or an unforeseen medical condition occurs in a family. They want to be assured that there are accessible, effective treatments immediately available to the family. Banking your baby’s cord blood offers you with life-giving stem cells and gives reassurance knowing that you can access your baby’s preserved stem cells at any time. Cord blood transplants have been proven effective in treating these conditions: Blood Disorders Acute Myelofibrosis Agnogenic Myeloid Metaplasia (Myelofibrosis) Amyloidosis Aplastic Anemia (Severe) Beta Thalassemia Major Blackfan-Diamond Anemia Congenital Amegakaryocytic Thrombocytopenia (CAT) Congenital Cytopenia Congenital Dyserythropoietic Anemia Dyskeratosis Congenita Essential Thrombocythemia Fanconi Anemia Glanzmann’s Thrombasthenia Myelodysplastic Syndrome Paroxysmal Nocturnal Hemoglobinuria (PNH) Polycythemia Vera Pure Red Cell Aplasia Refractory Anemia with Excess Blasts (RAEB) Refractory Anemia with Excess Blasts in Transition (RAEB-T) Refractory Anemia with Ringed Sideroblasts (RARS) Shwachman-Diamond Syndrome Sickle Cell Disease Cancers Acute Biphenotypic Leukemia Acute Lymphocytic Leukemia (ALL) Acute Myelogenous Leukemia (AML) Acute Undifferentiated Leukemia Adult T Cell Leukemia/Lymphoma Chronic Active Epstein Barr Chronic Lymphocytic Leukemia (CLL) Chronic Myelogenous Leukemia (CML) Chronic Myelomonocytic Leukemia (CMML) Ewing Sarcoma Hodgkin’s Lymphoma Juvenile Chronic Myelogenous Leukemia (JCML) Juvenile Myelomonocytic Leukemia (JMML) Myeloid/Natural Killer (NK) Cell PrecursorAcute Leukemia Non-Hodgkin’s Lymphoma Prolymphocytic Leukemia Plasma Cell Leukemia Leukocyte Adhesion Deficiency Multiple Myeloma Neuroblastoma Rhabdomyosarcoma Thymoma (Thymic Carcinoma) Waldenstrom’s Macroglobulinemia Wilms Tumor Immune Disorders Adenosine Deaminase Deficiency (SCID) Bare Lymphocyte Syndrome (SCID) Chediak-Higashi Syndrome (SCID) Chronic Granulomatous Disease Congenital Neutropenia DiGeorge Syndrome Evans Syndrome Fucosidosis Hemophagocytic Lymphohistiocytosis (HLH) Hemophagocytosis Langerhans’ Cell Histiocytosis (Histiocytosis X) IKK Gamma Deficiency (NEMO Deficiency) Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-linked (IPEX) Syndrome Kostmann Syndrome (SCID) Myelokathexis Omenn Syndrome (SCID) Phosphorylase Deficiency (SCID) Purine Nucleoside (SCID) Reticular Dysgenesis (SCID) Severe Combined Immunodeficiency Diseases (SCID) Thymic Dysplasia Wiskott-Aldrich Syndrome X-linked Agammaglobulinemia X-Linked Hyper IgM Syndrome X-Linked Lymphoproliferative Disorder Metabolic Disorders Congenital Erythropoietic Porphyria (Gunther Disease) Gaucher Disease Hunter Syndrome (MPS-II) Hurler Syndrome (MPS-IH) Krabbe Disease Lesch-Nyhan Syndrome Mannosidosis Maroteaux-Lamy Syndrome (MPS-VI) Metachromatic Leukodystrophy Mucolipidosis II (I-cell Disease) Neuronal Ceroid Lipofuscinosis (Batten Disease) Niemann-Pick Disease Sandhoff Disease Sanfilippo Syndrome (MPS-III) Scheie Syndrome (MPS-IS) Sly Syndrome (MPS-VII) Tay Sachs Wolman Disease X-Linked Adrenoleukodystrophy Further reading: https://www.lls.org/facts-and-statistics https://priorityyoumd.com/what-is-the-success-rate-of-stem-cell-therapy/

Parenting Hub

IS GAMING GOOD OR BAD FOR YOUR MENTAL HEALTH?

Affinity Health, a leading provider of high-quality health coverage, debunks common myths about the impact gaming has on your mental health. “Video games have evolved tremendously, going from basic pixelated diversions to captivating digital realms,” says Murray Hewlett, CEO of Affinity Health. “As they’ve soared in popularity, conversations about how gaming affects mental health have gained traction. Some believe gaming can be a therapeutic outlet, while others raise concerns about potential negative consequences. The link between gaming and mental well-being has also shone a spotlight on common myths.” Myth 1: Gaming Can Lead to Anti-Social Behaviour One common belief about gaming is that it’s a lonely activity that keeps people away from real-life connections. In truth, many of today’s video games encourage social interaction. Games like Fortnite, League of Legends, or Among Us allow players to connect online with friends and strangers. These connections foster a sense of belonging and friendship and alleviate loneliness. Myth 2: Gaming Leads to Aggression Numerous studies have explored whether violent video games cause real-world aggression and violence, but the results are inconclusive. The American Psychological Association suggests that while some studies indicate a link between violent video games and increased aggression, the overall effect size is relatively small. Family environment, upbringing, and individual personality play more substantial roles in aggression than video games alone. Myth 3: Gamers Are Lazy and Unproductive The stereotype of gamers as lazy and unproductive individuals who spend their days in front of screens persists. However, this myth overlooks the diverse and multifaceted nature of the gaming community. Gaming often involves complex challenges that require strategic thinking, teamwork, and perseverance. Competitive gaming, known as eSports, has become a legitimate career path, with professional gamers practising for hours daily to excel in tournaments. Additionally, gaming can enhance cognitive skills, such as problem-solving, decision-making, and spatial awareness. Myth 4: Gaming Addiction Is Not a Real Problem Gaming addiction, often referred to as Gaming Disorder, is a natural and recognised mental health condition. In 2019, the World Health Organisation (WHO) included gaming disorders in the International Classification of Diseases. Gaming Disorder is defined by decreased control over gaming, a preference for gaming over other activities, and persistent gaming despite detrimental implications to one’s physical or mental health. While it affects a relatively small percentage of gamers, it can seriously affect their lives. Acknowledging the existence of Gaming Disorder is crucial for early diagnosis and intervention. Myth 5: Gaming Always Causes Sleep Problems Excessive gaming, particularly late at night, can disrupt sleep patterns. However, many other activities, such as binge-watching TV shows or using smartphones before bedtime, can also disrupt sleep. The key is moderation and responsible gaming habits. Benefits of Gaming on Mental Health  Now that we’ve debunked some common myths, let’s explore the potential positive effects of gaming on mental health: Stress Reduction: Gaming can serve as escapism, allowing individuals to detach from real-life stressors and unwind temporarily. Cognitive Enhancement: Many video games require problem-solving, critical thinking, and multitasking, which can enhance cognitive abilities. Social Connection: Online multiplayer games enable players to connect with friends and meet new people, fostering a sense of belonging. Creativity: Games that involve building, crafting, or storytelling can stimulate creativity and imagination. Mental Resilience: Overcoming challenges in video games can promote resilience and the ability to handle real-life adversity. Therapeutic Applications: Some video games are specifically designed for therapeutic purposes, such as managing anxiety or post-traumatic stress disorder (PTSD). Community Support: Gaming communities often provide emotional support and a sense of camaraderie among players facing similar challenges. Balancing Act: Responsible Gaming While gaming can offer mental health benefits, it’s essential to strike a balance and practice responsible gaming. Here are some tips: Set Time Limits: Allocate a specific amount of time for gaming each day and stick to it. Prioritise Real-Life Activities: Ensure that gaming doesn’t interfere with essential daily activities, such as work, school, exercise, and social interactions. Take Breaks: Regularly step away from the screen to rest your eyes and stretch your body. Monitor Content: Be mindful of the content and age-appropriateness of the games you play, especially if you have children. Seek Professional Help: If you suspect you have a gaming addiction or notice signs of its negative impact on your life, consult a mental health professional.

Bonitas – innovation, life stages and quality care

Pregnancy, your body and your baby – week 14 of your pregnancy

Week 14 of your pregnancy and you’re in month four of your pregnancy with five to go – almost half way already. Trimester two of pregnancy means you should be feeling renewed levels of energy and you may even notice that your appetite has increased thanks to morning sickness slowly easing up. Your baby in week 14 Your baby is now the size of a peach, and now often moves her arms and legs – but you won’t be able to feel this yet. If you could see into your belly, you may even notice your little one sucking their thumb! Around this time the grasp reflex is evolving, and hair growth is starting as follicle under the skin, so that when they’re born your baby should have silky strands of hair. Your little one’s genitals are now also fully developed, but it’ll still be difficult to tell their gender on ultrasound. Your body in week 14 Luckily during your second trimester you’ll be feeling more yourself, with rising energy levels, breasts that are less tender and dissipating nausea. You’ll also probably starting to show a bit as well, however, some moms, especially those expecting multiples, may start showing sooner. This is because your uterus is rising out of the pelvic region and into your lower abdomen. During the second trimester you’ll also notice that you’ll start to put on weight, don’t be alarmed by this as it’s completely normal and healthy during a pregnancy. Things to take note of  If you found that during your first trimester your pregnancy symptoms meant that you generally stayed away from exercise, embrace your renewed energy levels and start doing gentle exercises such as water aerobics, prenatal exercise classes and gentle walks. This’ll be beneficial to both you and your growing little one.

Parenting Hub

How to get healthier gums in 14 days

The popularity of water flossers is growing, with TikTok videos going viral, and for good reason! Water flossing for one minute before brushing easily removes bacteria and debris from hard-to-reach areas deep between teeth and below the gumline where traditional brushing and flossing can’t reach. The patented pulsating, massaging action increases circulation and gum health. However, not all water flossers are made equal. During clinical trials, the Waterpik® Water Flosser was found to be Twice as Effective as String Floss for Reducing Gingival Bleeding.  Reduction of Gingival Bleeding – 14 Day Results:   After 14 days, used in conjunction with manual tooth brushing, the Waterpik® Water Flosser with the Classic Jet Tip was twice as effective as traditional floss at reducing gingival bleeding. At 30 days, the relative improvement in gingival bleeding for the Water Flosser groups was even more dramatic. There were no significant differences between the Water Flosser Classic Jet Tip and the Plaque Seeker® Tip. The Waterpik® water flosser is clinically proven to provide significant oral health benefits: Improve gum health Remove plaque and bacteria Reach areas that you can’t get to with a toothbrush or string floss Removes up to 99.99% of plaque from treated areas Up to 2X as effective for implants vs String Floss Up to 3X as effective for Braces vs String Floss Up to 50% more effective for Gum Health vs String Floss The sleek and easy to use Waterpik® water flosser is ideal for implants, and essential for braces. Join the revolution – add the Waterpik® Water Flosser to your daily routine and choose the Waterpik® that suits your bathroom and lifestyle. Waterpik® WP-490 Cordless Plus Water Flosser – R1,599.00  Rechargeable and portable, the WP-490 Cordless Plus water flosser is ideal for the traveller and smaller bathrooms. It is rechargeable with ultra-quiet technology. The ergonomic narrow hand grip gives easy-to-hold control with improved tip rotation. This model comes with 2 pressure settings, 360-degree tip rotation, four tips and global voltage. Why would you benefit from using the WP-490? Effective plaque removal – It removes up to 99.9% of plaque from treated areas. Healthier gums – Clinically proven to be up to 50% more effective for improving gum health compared to string floss. Ideal for implants – Clinically proven to be up to 2x as effective for improving gum health around implants compared to string floss using the Plaque seeker™ tip. Essential for braces – Clinically proven to be up to 3x as effective for removing plaque around braces compared to string floss using the orthodontic tip. Helps to prevent bad breath, gum disease, and tooth decay – Removes plaque and debris from deep between teeth and below the gumline where brushing and traditional flossing can’t reach. Leaves your mouth feeling fresh and clean. Great for people with braces, implants, crowns, bridges, and veneers.   WP-462 Cordless Plus Black Water Flosser – R1,599.00 The WP-462 Cordless Plus Black water flosser with its satin finish takes up little space and include four unique tips to clean deep between teeth and below the gumline where traditional string floss can’t reach. Classic Jet tip – general use. Plaque Seeker tip – best for implants, crowns, veneers and bridges and removes plaque in hard-to-reach areas. Orthodontic tip – ideal for braces and is 3x as effective as floss for removing plaque around orthodontic appliances. Tongue cleaner – removes bacteria from the tongue to freshen breath. The advanced dual water pressure control system of the Cordless Plus allows you to adjust water pressure intensity according to your preference. The design is ergonomic and includes an easy-to-fill reservoir and a rechargeable battery. Waterpik® is the #1 recommended water flosser brand, clinically proven to remove up to 99.9% of plaque from treated areas. It is up to 50% more effective for improving gum health compared to string floss. To view and shop Waterpik® products, visit www.waterpikflosser.co.za. Also available at selected dentists, Dis-Chem stores and Takealot.

Parenting Hub

Fetal MRI: Insights from a specialist

When an unborn baby has an abnormality, decisions about the delivery and neonatal care can often be planned in advance – with the help of an MRI. However, MRI image acquisition can be tricky and quality reporting is an acquired skill. Dr Lauren Raubenheimer is an expert in the field, having honed her skills in London under word-renowned fetal and neonatal imaging specialist, Prof. Mary Rutherford.  She recently joined SCP Radiology as a consulting radiologist and provides insights into fetal MRI and what it can mean to expecting couples and their healthcare providers. ‘When a couple discovers the baby that they carry has an abnormality, the impact is enormous and can be life changing. As a mother, I have a huge emotional investment in my work. I hope that my findings give parents more answers as they navigate a difficult path.’ She says that, in many cases, the timing and route of delivery, as well as the neonatal care that will be required, can be planned in advance with help from an MRI. ‘Nothing is better than confirming a minor abnormality, with a good prognosis and giving parents some reassurance.’ Here she talks about the how, why and when a fetal MRI is indicated and the safety factors taken into consideration when doing so. When would fetal MRI be recommended? Patients are typically referred from Fetal Medicine Specialists after an abnormality has been detected on a screening ultrasound. An MRI can be done to confirm the abnormality, as well as to assess for abnormalities that are not readily visible through standard imaging techniques. This can significantly affect the prognosis. A fetal MRI can be performed either in the second or third trimester. ‘My special interest is in developmental fetal brain abnormalities but I also perform MRIs for body abnormalities, including congenital diaphragmatic hernia, congenital lung lesions, spina bifida, kidney anomalies and fetal tumours.’ Why not ultrasound? MRI can be superior to an ultrasound in certain instances. Such as assessing the folding of the brain and assessing parts of the brain obscured by the skull, when amniotic fluid is low (amniotic fluid is a clear to slightly yellow liquid that cushions a fetus within the amniotic sac) and when mothers have a high body mass index (BMI). How are quality images obtained? Fetal movement has previously been an obstacle in getting good quality MR images in the past. ‘But with today’s magnets and the use of faster imaging sequences, we can obtain excellent image quality, she explains. That said, a very busy baby calls for considerable skill and patience from the radiographer and, at SCP Radiology, fetal MRI scans are done exclusively by the lead MRI radiographer, Andrea Nagel. Safety comes first Safety is of utmost importance.  Present data shows ‘no conclusively documented harmful effects of MRI imaging on the developing fetus, providing it is at the safe and optimal level (1.5 T”)’. For the peace of mind of expectant parents, Dr Raubenheimer adds that MRI does not use ionising radiation and intravenous contrast is not administered in fetal MRI. ‘By working within strict parameters, potential harm to the fetus is prevented’. About referral and funding Fetal MRI is covered by medical aids but, as is the case with all other MRI scans, preauthorisation is required.. It is preferable that patients are referred from a Fetal Medicine Specialist after a detailed ultrasound. ‘Having access to ultrasound reports and knowing the exact gestation is crucial to an accurate MRI report’, Dr Raubenheimer emphasises. In general, she is in close communication with her colleagues in fetal medicine when it comes to individual patients. Parents who want to read more about the safety of and preparation for fetal MRI, can download SCP’s information sheet from the website: www.scp.co.za About Dr Lauren Raubenheimer Dr Raubenheimer obtained her MBChB with first class honours from the University of Cape Town and her radiology qualification with distinction from the same institution. After graduating, she worked in both the public and private sectors in South Africa and developed a special interest in fetal imaging and neuroradiology. She enrolled for the European Diploma in Neuroradiology (EDiNR) and, in 2019, did an observership in fetal and neonatal brain MRI at the St Thomas’ Hospital Centre for the Developing Brain in London, under the guidance of Prof. Rutherford. Since then, she has reported fetal MRIs for Groote Schuur Hospital, as a volunteer medical specialist from 2019 to 2023 as well as private-sector fetal MRIs, first in Stellenbosch and more recently at Mediclinic Cape Gate in partnership with SCP. Aside from her fetal imaging work, she also currently does contract reporting for an international radiology provider.

Parenting Hub

Sleepless Nights: Understanding and Addressing Pain and Fever in Children

There’s no “right” moment for pain and fever to strike. Yet, when they jolt your child awake in the wee hours, the challenge often feels magnified. Understanding the symptoms of pain and fever and knowing how to address them can make the experience less daunting for everyone involved. Why Do Children Experience Fever? Fever in children is defined as a temperature of 37.8°C or higher.1a It’s essential to understand that a fever is not an illness. Instead, it’s like the body’s alarm system, indicating that it’s actively confronting an illness or infection.1b  This natural response serves a crucial purpose; it kickstarts the immune system, mobilising it to fend off invaders. In essence, when the body’s temperature rises, it’s creating an environment that’s less hospitable to germs.1c However, as beneficial as this might be internally, it’s not always a comfortable experience for our young ones. The elevated temperatures can lead to feelings of unease, discomfort, and restlessness, which can be concerning for parents and caregivers.1d Why Do Children Experience Pain? Pain in children can stem from multiple causes. Some of the straightforward causes include the usual bumps and scrapes that come with active play2a or the common headaches that might stem from a long day2b. There are also those tummy troubles which can range from a simple upset stomach to more severe aches2c. Various infectious illnesses can also be culprits, such as ear infections, strep throat, pesky stomach bugs, skin infections, and even pneumonia2d. Don’t forget the short-lived but often sharp pain that accompanies immunisations2e, and for our littlest ones, the discomfort of teething 2f.  How Pain and Fever Can Impact Your Child’s Sleep We all know that a child’s sleep is crucial for their physical growth, mental development, and overall well-being.3 However, when they’re unwell, their sleep can get disrupted. The goal is about reducing your kiddo’s distress and increasing their comfort so they can get a better night’s sleep. How to Help Your Child If pain or fever is bothering your child, it’s crucial to address it promptly and appropriately. Here are a few ways to provide relief: Fluids: Keep the juice and water coming! A fever can lead to dehydration, so make sure they’re drinking often and staying hydrated.4a Bathing: A tepid bath can do wonders to cool a feverish child down. Just remember, cold water or rubbing alcohol are no-nos. They can be harmful!4b Dress Code: Think summer vibes. Toss out the heavy PJs and let them wear something breezy and light.4c Snuggle Essentials: If they’re feeling a bit chilly, drape them with a light sheet. It’s all about keeping them cozy!4d The Power of Panado®: Always choose a pain and fever medication that is suitable for your child’s age and weight and measure the dose accurately: Always check the label or call your paediatrician for the correct dosage for your child.4e  Dosage details for the Panado®  range of products can be found at   https://panado.co.za/dosage-calculator/ and are calculated according to your child’s age and weight. A fever should naturally break on its own in one to three days, but you will want to seek out your paediatrician if your child’s fever persists.4f Turn to the Power of Panado® Paediatric Range of Products Panado®  contains paracetamol, which boasts over 150 years of clinical experience.5  It’s fast-acting6 and gentle on sensitive tummies.7 Panado®  paediatric range of products includes Panado®  Paediatric Syrup, Strawberry,8 Panado®  Paediatric Syrup, Peppermint Alcohol and Sugar-Free,9 Panado® Paediatric Syrup, Peppermint 5 ml Sachets10, Panado®  Infant Drops11 and recently launched Panado® Grape flavour which colourant-free, tartrazine-free, alcohol-free, and sugar-free.13 Parents trust12 Panado®  for the power to fight their little one’s pain and provide fast6 relief when needed most.  Panado® products are available at Baby City, Pick n Pay, Checkers, including Hypers, Shoprite, Clicks, Dis-Chem, and Independent Pharmacies. For more information, visit visit https://panado.co.za/ and join the conversations on Facebook.   2023083110309095   References:   University of Rochester Medical Center. Fever in children. Available from:  https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=90&contentid=P02512. Last accessed August 2023. UPMC Health Beat. Types of pain in children and how to treat it. Available from: https://share.upmc.com/2017/02/pain-in-children/. Last accessed August 2023. Johns Hopkins All Children’s Hospital. The importance of sleep for kids. Available from: https://www.hopkinsallchildrens.org/ACH-News/General-News/The-importance-of-sleep-for-kids. Last accessed August 2023. Children’s Health. What to do when your child has a fever. Available from: https://www.childrens.com/health-wellness/what-to-do-when-your-child-has-a-fever. Last accessed August 2023. 150 years of paracetamol. GP Pharma Update Mar/Apr 2019 Moller PL, Sindet-Pedersen S, Petersen CT, et al. Onset of acetaminophen analgesia: Comparison of oral and intravenous routes after third molar surgery. Br J Anaesth 2005;94(5):642-8. doi:10.1093/bja/aei109. Available from: https://pubmed.ncbi.nlm.nih.gov/15790675/. Last accessed August 2023. Goodman & Gilman’s.The pharmacological basis of therapeutics, 13th ed. Acetaminophen. p696 Panado® Paediatric Strawberry Syrup approved package insert, March 2002. Panado® Paediatric Syrup Alcohol and Sugar-Free professional information, May 2022. Panado® Paediatric Syrup professional information, May 2022. Panado® Infant Drops (Drops) approved professional information, August 1990. Circana, MT,  October 2023 MAT. Panado ® Paediatric Alcohol Free – Grape Flavour. Approved package insert. October 2022.

CRYOSAVE

Cord Blood- and Tissue-Derived Stem Cells: Can Autism be treated?

Autism Spectrum Disorder (ASD) is a complex neurological condition that usually develops in childhood. ASD is a neurodevelopmental disorder characterized by difficulties with social interactions and communication and the presence of repetitive and restricted behaviours.  As awareness about the condition has grown, so has the recognition that autism isn’t an intellectual disability and can occur in people with average and above-average IQs. Autism diagnosis rates have tripled in less than two decades. Approximately 1 in 44 children are identified as having ASD. Boys are four times more likely than girls to be diagnosed with autism. Autism affects all ethnic and socio-economic groups. Most ASD cases are idiopathic (a disease or condition which arises spontaneously or for which the cause is unknown). Approximately 15% to 20% of ASD cases are caused by specific genetic mutations. Some of the genes involved in ASD include ADNP, ARID1B, ASH1L, CHD2, CHD8, DYRK1A, POGZ, SHANK3, and SYNGAP1. In most individuals with ASD caused by rare gene mutations, the mutations occur in only a single gene. Both, 16p11. 2 deletion and duplication have been associated with the risk for autism spectrum disorder (ASD). Other deletions that are associated with ASD are 3q29 deletion and 1q21.1 deletion. There is no cure for Autism, however, various treatments and therapies assist with the day-to-day lives of people with ASD. Currently, several clinical trials are investigating the use of stem cells derived from cord blood and/or cord tissue. These trials are designed to ease or decrease the symptoms of ASD and are not cures. In future, there remains a strong need to generate supporting scientific data on stem cell therapy for use in ASD. The studies that have been conducted thus far, showing proof of clinical improvement, have not been standardised, there is therefore a need to collect further data. Various stem cell types have been used, and different routes of administration (intravenous/intrathecal), dosage levels, and duration of treatment were used. Additionally, the time to follow-up needs to be more standardised, and only then will it allow for the accurate assessment of long-term outcomes and comparisons of different choices and procedures of transplantations with respect to ASD treatment. Clinical studies have been undertaken using different sources of stem cells, i.e. bone-marrow, umbilical cord blood-derived stem cells, and cord tissue-derived stem cells. These studies focused on alleviating ASD symptoms by modulating inflammatory processes in the brain. In most of these studies, significant improvements were reported in the first few month’s post-infusion. These were also sustained and measurable after 12 months.  Children with higher baseline nonverbal intelligence percentages showed greater improvement. The clinical studies mentioned above reported no severe adverse events after cell transplantation and encountered only minor adverse events, such as nausea, vomiting, and pain at the site of injection. These preliminary clinical trials provide us with an encouraging opportunity for the application of stem cell therapy in the treatment of ASD. However, only with additional neuro-rehabilitation such as behavioural and speech therapy, sensory integration, or psychological intervention, etc., which will support the efficacy of stem cell therapy, will the full potential of this type of treatment of ASD be realised. Breaking news (2022): Rutgers scientists studied neural precursor cells (NPCs) – of patients with ASD. They discovered the NPCs – that create the three main kinds of brain cells: neurons, oligodendrocytes, and astrocytes – either overproduced or underproduced the number of permanent brain cells. These NPCs are formed prenatally during a period that stretches from the end of the first trimester through the second, about weeks eight to 24 of the 40-week gestation period of a human fetus. The scientists say this data might in the future assist in identifying a  “biomarker, which could signal when to introduce therapy or to identify signalling pathways for drug targeting in future.” References Lord C, Risi S, DiLavore PS, Shulman C, Thurm A, Pickles A. Autism from 2 to 9 years of age. Arch Gen Psychiatry. 2006 Jun;63(6):694-701. Hyman, S.L., Levy, S.E., Myers, S.M., & AAP Council on Children with Disabilities, Section on developmental and behavioural paediatrics. (2020). Identification, evaluation, and management of children with autism spectrum disorder. Paediatrics, 145(1), e20193447. https://www.rutgers.edu/news/stem-cells-either-overproduce-or-underproduce-brain-cells-autistic-patients

Bonitas – innovation, life stages and quality care

Pregnancy, your body and your baby – week 13 of your pregnancy

At week 13 of your pregnancy you are now in your second trimester. This trimester is often nicknamed the honeymoon period, as your pregnancy symptoms should have started easing up, and your baby is still small enough that you don’t feel uncomfortable. Your body at week 13 At week 13 your energy levels should start increasing, but if your nausea and fatigue don’t disappear just yet – don’t despair, some moms experience these for longer than others. This increase in energy won’t stick around forever, so make the most of this time while you can and tick important to-dos off your list. Your blood flow will also increase during this time, and because of this you may see blue streaks under your skin from your veins and experience an increase in libido. Your baby at week 13  Your baby is now the size of a lemon and her body proportion is slowly starting to change, although the head is still the biggest part of the body. Your baby is growing rapidly,  and during this time, her intestines are moving from the umbilical cord into the stomach. Her eyelids are shut to protect the eyes as they develop and her vocal cords are also developing, so that when your baby is born she’ll be able to cry and laugh and eventually say her first word. Things to remember in this week  Around this time is when some people choose to tell family, friends and employers that they’re expecting. You should pick when you feel most comfortable to tell everyone, however, this time is often chosen, as your risk of miscarriage will have decreased and you’ll have had your first pregnancy ultrasound, which should confirm that your baby is healthy.

Vital Baby

Motherhood & the Pressure to Conform to Unrealistic Body Images

Motherhood is a transformative journey, a unique experience that shapes each woman in remarkable ways. In today’s world, where social pressures abound, it’s essential to recognise the impact of unrealistic body standards on new mothers during pregnancy and postpartum. Many mums-to-be embrace their growing bellies, celebrating the life within, proudly displaying their baby bumps and appreciating the miracle of pregnancy. Other mums, however, may feel alienated from these changes and out of control of the adjustments taking place both inside and outside their bodies. Experiencing dissatisfaction with one’s body during pregnancy can have significant implications for both maternal and foetal well-being, leading some women to adopt extreme dietary restrictions or even trigger a relapse of an existing eating disorder.  One’s self-esteem can be further impacted when comparing oneself to unrealistic portrayals of pregnant women in the media, where stretch marks and uneven skin tone have been edited out. After birth, an obsession to ‘return to normal’ can be as damaging, leaving new mums feeling pessimistic and depressed about themselves instead of accepting that motherhood has upgraded them to a new life stage and status. The reality is that the ‘perfect’ pregnancy body doesn’t exist. The true beauty of birth into motherhood lies in your authenticity. Understand that it’s normal to have mixed feelings about your changing body during pregnancy. Many women go through similar emotions. If you feel inadequate or negative about yourself, it can help to: #1 Shift your mindset from aesthetics to functionality. Marvel at how your body is preparing to grow and deliver a new life into the world. #2 Share your feelings with a trusted friend, partner, or family member. Talking openly can help lighten your mental load. #3 Take the time to honour yourself by appreciating the strength, endurance, and resilience your body exhibits during pregnancy and childbirth.   #4 See it as an invitation to educate yourself and learn about the changes your body will undergo during pregnancy and postpartum so you can balance and support your mind and body better. #5 Create a pregnancy mantra or positive phrase. Repeat it regularly, especially when feeling low, and practise better self-talk. Dispelling Fears & Myths: Pregnancy brings significant changes in all areas of one’s life, and the fear of the unknown may cause anxiety. As your body goes through the gestation phase, you will experience hormonal shifts, weight gain, bloating, mood swings, swollen feet, back pain, morning sickness and skin changes that can make some women feel helpless and overwhelmed.  While you may witness your favourite celebrity or influencer appearing to breeze through their pregnancy with perfect glamour, you are not seeing the full story of real life; everyone has low days where our biorhythms are on the fritz. Understand it is the media’s job to photoshop and gloss up for the best aesthetic look rather than reveal the everyday practical challenges.  Challenge the myths circulating in women’s conversations and challenge yourself to decide what is true for you. For example: Myth: Pregnancy Makes You Hungrier: True. Pregnancy hormones often lead to an increased appetite; this is a natural body indicator for more fuel as you use more energy to grow a new person. Having more significant portions is normal. Myth: You Need to Eat for Two: False. There’s no need to eat for two. Only in your third trimester do you need about 200 extra calories per day. Focus on a balanced diet and quality nutrition, which will satisfy you more. Myth: You Should Gain a Kilogram a Month Throughout Pregnancy. Not exactly. Weight gain in pregnancy doesn’t happen evenly; most pregnancy weight happens after 20 weeks, and the recommended weight gain during pregnancy varies based on your pre-pregnancy weight and body mass index (BMI). On average, expect to gain 1 to 1.5 kilograms in the first three months (more if expecting twins) and 1.5 to 2 kilograms each month until delivery.   Myth: Excessive Weight Gain Is Fine. False. Too much weight gain puts you at risk for gestational diabetes and preeclampsia. Aim for 11 to 16 kilograms (more for twins) if you are of average weight and height.  How to Embrace Your Changing Body Focus on nourishing your body with wholesome foods and staying active—your well-being matters. Weight gain, stretch marks, and loose skin are natural parts of pregnancy like age is a natural part of life.  Your growing belly is a testament to the life blossoming within. Each stretch mark tells a story of strength. See this period as a call to walk your path rather than following another. Appreciate motherhood as an opportunity to create a closer relationship with yourself as you take on the responsibility of nurturing another tiny human being.   Prioritise your well-being rather than focussing on attaining a specific appearance. Understand that your body is doing incredible work, and imperfections are okay. Consult a healthcare provider who can guide you through the physical changes and address weight concerns.  Knowledge is empowering; learn about the changes you’ll experience with the support of the Vital Baby social media accounts, and connect to Sr Londe online, Vital Baby’s trusted advisor who provides advice through monthly Instagram Live videos for new mums and mums-to-be, answering your specific questions during the sessions. Connect to other Moms and join support groups and online communities where you can share experiences and hear stories from other women, which can normalise the challenges and help you feel less alone.  As the journey of motherhood unfolds, Vital Baby stands alongside expectant mothers, offering support, encouragement, and a celebration of the incredible transformations that occur during pregnancy and childbirth. We encourage new moms to focus on their body’s remarkable achievements and know that every curve, and every scar tells a story of resilience and love. Together, let’s redefine beauty beyond the superficial and honour the miraculous transformations that occur during the sacred journey of motherhood.

Philips Avent

Affordable ways to maximise your nutrition during pregnancy

As South African consumers we have become accustomed to the term ‘tightening your belt’ which means to live more frugally and to spend money wisely in this cash strapped economy. South African’s spend on average around R1403 per month on groceries, that can be compounded by the stress of other monthly expenses specifically when one is trying to make better food choices and save for a growing family. Considering this, here are a few actionable tips to help expectant mothers in maintain a healthy diet by making strategic choices and using available resources to ensure that your developing baby gets all the nutrients needed without breaking the bank. Plan your meals Planning your meals in advance will help you make sure you have all the necessary ingredients, avoid impulse buys, and stay within your budget. You can create a budget-friendly shopping list by including affordable yet nutritious items that provide all the nutrients for your growing baby and provide satiety for mum. Look at simple, cost-effective meals by adopting small habits like avoiding pre-packed portions or doing a weekly scan of supermarket savings to stretch your rand further. Having a written list makes it easier to analyse your food intake and will help you avoid food and financial waste. Instead of wasting food, find ways to repurpose and use leftovers. For example, leftover vegetables can be turned into a stir-fry or soup, and leftover meat can be added to salads or sandwiches. Keep it homegrown Local markets and street vendors often offer fresh produce at lower prices compared to supermarkets. By shopping at these places, you can save money while still getting fresh and nutritious ingredients for your meals. Consider planting a small kitchen garden where you can grow your own fruits, vegetables, and herbs which can be a cost-effective way to supplement your diet with fresh and nutritious foods. Fruits and vegetables are packed with essential vitamins and minerals such as vitamins A, B, C and E; folic acid and calcium that are important for a healthy pregnancy. Your baby is what you eat Protein is an essential nutrient during pregnancy, but it can also be expensive. To ensure you are getting enough protein without breaking the bank, opt for affordable protein sources such as beans, lentils, eggs, and canned fish like sardines or pilchards. Avoid processed foods as they tend to be more expensive and often lack nutritional value. Rather incorporate affordable staple foods such as maize meal, rice, and potatoes into your diet, these foods are often budget-friendly and provide necessary carbohydrates for energy. Water is an essential component of a healthy diet, especially during pregnancy. Make water your main beverage and avoid sugary drinks, which can be expensive and provide empty calories. You can also download the Philips Pregnancy+ app which is an additional valuable resource for expectant parents. The app supports parents and baby in a healthy and safe pregnancy and provides a comprehensive guide through all stages of pregnancy. “We’ve been helping families around the world for over 100 years, and we know that nourishing your body is important for the health and safety of you and your baby. Prioritising certain food groups, managing portions, and staying within a budget ensures that you and your baby receive the necessary nutrients for optimal health and development,” says Nelisiwe Xundu Consumer Marketing Lead: Personal Health Africa.

Dr Candice Shah

Children and nutrition

Adequate baby and child nutrition is imperative in order to achieve appropriate growth & development, build defence against infections and to decrease the overall incidence of life-threatening disease in childhood. Approximate energy, protein, iron, and folate requirements during childhood Age Energy kJ/day Protein g/day Iron mg/day Folate mcg/day 0-6 months 2700 13 6 65 7-12 months 3500 14 10 80 1-3 years 5500 23 10 150 4-8 years 7000 30 10 200 9-13 years 10000 45 18 300 (Adapted from the National Academy of Sciences- USA) Baby nutrition (0-6 months)  During the first 6 months of life most nutrient requirements are met by exclusive breastfeeding. Babies should thereafter be weaned onto solid foods such as vegetable feeds and cereals. It is important to view weaning as both a nutritional and developmental experience as babies explore various tastes and textures. Breastmilk is advantageous because it contains several active enzymes, hormones, and growth factors. Breastmilk also has antibacterial and antiviral properties. Research has also shown that breastfeeding can delay the onset of allergy. The Baby Friendly Hospital Initiative (BFHI) was launched in 1991 by the World Health Organization to support breastfeeding mothers. Infant and toddler nutrition (1-3 years) This age group requires a good balance between breastfeeding and complementary feeds. It is recommended to start with a few teaspoons of nutrient dense food prepared hygienically. It is important to track the weight of the child during this crucial period of weaning. Food fortification is another implementation that helps prevent iron deficiency and nutritional anaemia. Child and teenager nutrition (5-12 years) Eating habits developed during this stage of development sets the scene for the approach to food well into adulthood. Encouraging three healthy meals a day is recommended but appetite may decrease during this phase which may worry parents. However, the incidence of childhood obesity is on the rise in South Africa which can put children and teenagers at significant risk for chronic conditions such as type 2 diabetes and hypertension.  Malnutrition Malnutrition may present as an abnormally high or low body mass, poor growth, failure to thrive, swelling of soft tissue (oedema) and recurrent infections due to a compromised immune system. Inappropriate intake of energy and protein may lead to malnutrition. Furthermore, certain micronutrient deficiencies may lead to unique signs & symptoms, such as Vitamin A deficiency or iron deficiency.  Protein energy malnutrition (PEM) This type of malnutrition depends on how long protein and energy has been insufficient for the child. Other factors that impact the severity of PEM include age of the child and other associated vitamin, mineral and trace element deficiencies. It is vital to keep track of a child’s weight for height which can be a useful indicator of protein and energy intake.  Vitamin A deficiency  Vitamin A is found in milk, egg yolk, fish oils, some vegetables and fruits. The diets of children with Vitamin A deficiency are often deficient in other nutrients. A deficiency in Vitamin A can cause dry eyes, night blindness and an increase in the severity of serious infections. Research has shown that Vitamin A supplementation during complicated measles decreases the duration of complications. If Vitamin A deficiency is suspected, a dose of Vitamin A should be given immediately. Vitamin A should be made easily available for children at local clinics and hospitals. Diets rich in Vitamin A containing foods should be encouraged such as green leafy vegetables, pumpkin, squash and carrots. Vitamin B complex deficiency Vitamin B complex can protect against disease and is essential for metabolic processes. Some signs of Vitamin B complex deficiency include dermatitis, diarrhoea, dementia, mood instability and anaemia. Good food sources of B vitamins include, meat (especially liver), seafood, poultry, eggs, dairy products, legumes, leafy greens and seeds. Vitamin C deficiency Vitamin C facilitates the absorption of iron. Interestingly, cow’s milk is low in Vitamin C and breastmilk is rich in Vitamin C. Other sources of Vitamin C are citrus fruits, broccoli, berries, melons, potatoes, papaya, guava and tomatoes. Vitamin C deficiency results in poor collagen, poor wound healing, bleeding and haemorrhage. Iron deficiency  This can occur commonly in especially the first year of life because milk is low in iron. Iron deficiency can lead to a poor immune system causing an increase in infections, gastrointestinal symptoms, impaired effective absorption of food and vitamins, impaired thermoregulation, fatigue, and impaired cognitive function.  Zinc deficiency Zinc is a trace element which aids in metabolic processes and immunity. It also helps maintain epithelial integrity and growth. Zinc deficiency is associated with growth faltering, low birth weight babies and skin lesions. Zinc supplementation is widely available for those children who may require it. Prevention of nutritional disorders Good health education as early as during and after pregnancy, at clinics and schools is critical. The use of Road to health booklets, growth and weight charts should be easily accessible in order to prevent malnutrition.  “My plate” is one tool accessible on www.myplate.gov. This resource will allow children to explore food ideas and serves as a visual reminder to make healthy food choices. Conclusion My hope is for all children to grow up healthily while cultivating a positive attitude towards food. Food is vital fuel providing energy that can allow our children to thrive if chosen appropriately and in the correct portion sizes. The caregiver is the most important individual in a child’s life. You can make it easier for your kids to choose healthy options by keeping fruits and vegetables on hand and nutrient-dense foods easily available in the home. Sit down as a family and indulge in nutritious, wholesome meals together. A balanced diet is a balanced body. Dr Candice Shah Specialist Paediatrician Netcare- N1 City Hospital, Cape Town

CRYOSAVE

A Journey of Hope: Xander Vermeulen’s Remarkable Path with CryoSave

In the intricate tapestry of medical advancements and human resilience, few stories resonated as deeply as that of Xander Vermeulen. Born a decade ago, Xander’s life took an unexpected turn when a severe open fracture left his left arm impaired. Yet, amidst the challenges, a glimmer of hope emerged through CryoSave—a decision made by his parents at his birth that would prove to be transformative. A Decade of Preparation – Xander’s journey with CryoSave began at birth, a decision by his parents to bank his stem cells—an investment in his future health. Little did they know, those tiny cells would one day hold the key to his rehabilitation. November 2020: A Turning Point – Tragedy struck in November 2020 when Xander suffered a severe open fracture on his left arm. The subsequent surgeries and skin grafts failed to restore full functionality, leaving Xander grappling with a disability that profoundly impacted his daily life. CryoSave Steps In – Amidst the uncertainty, CryoSave emerged as a beacon of hope. Through partnerships with surgeons and stem cell experts, CryoSave embarked on a mission to assist Xander in his journey towards rehabilitation. This collaboration marked the beginning of a remarkable chapter in Xander’s life. October 4, 2024: A Collective Effort – A significant update to Xander’s story unfolded as a team of medical professionals stepped forward to offer their expertise and resources pro bono. Dr. Deon Weyers, a specialised Plastic and Reconstructive Surgeon, led the charge in reconstructing Xander’s arm. Supported by Dr. Giancarlo Cavedon, a specialized Anesthetist, Kelly Glazebrook, an Occupational Therapist specialized in hand therapy, Paula MacClarin, along with her team of Physiotherapists, Adrian Singh, an Orthotist, and Cure Day Clinic, this collective effort underscored the power of collaboration in transforming lives. November 30, 2023: A Milestone Achieved – On this day, a significant milestone was reached as the first procedure—the placement of a tissue expander—took place. This pivotal moment symbolized a step forward in Xander’s journey towards arm rehabilitation, with stem cells poised to play a crucial role in his healing process. March 12, 2024: Progress and Optimism – As the expansion neared completion, optimism filled the air. With each passing day, Xander’s unwavering resilience served as a testament to the human spirit. The impending second procedure held the promise of further enhancing Xander’s quality of life, thanks to the dedication of CryoSave and its partners. March 20, 2024: A Moment of Triumph – The second procedure unfolded with precision and skill, as Dr. Deon Weyers conducted flap reconstruction on Xander’s arm. Enriched with Xander’s own stem cells, this innovative approach marked a triumph of science and compassion—a testament to the remarkable strides made in medical technology. As expectant parents prepare to welcome a new life into the world, the option of stem cell banking presents a unique opportunity to safeguard their child’s future health. This procedure, conducted directly after birth, is risk-free and painless for both mother and baby. By banking their child’s stem cells, parents are investing in a potential lifeline—a resource that may hold the key to unforeseen medical challenges down the road. As Xander’s story illustrates, the decision to bank stem cells is not merely a precautionary measure but a tangible expression of hope—a gift that has the power to shape the course of a child’s life for years to come.

Parenting Hub

Probiotics and Travel: Your Gut’s Best Friend On the Go

Travelling is an exciting adventure, but it can sometimes throw your digestive system off balance. Multi-strain probiotics contain a variety of live micoorganisms1a that provide health benefits,1b  including enhancing gut health1c while on the move. Benefits of Multi-Strain Probiotics The human digestive system is filled with hundreds of different types of tiny organisms living together in balance with one another.2a Most of these tiny organisms are bacteria.2b The types of bacteria in your gut can be influenced by various factors including what you eat. 2c Probiotic bacteria are like the good guys in this digestive ecosystem. They move in, take up residence, and help things run smoothly. They can help your digestive system work the way it’s supposed to.2d Probiotics can also lend a hand to your immune system,2e helping immune cells do their job better. Managing Irritable Bowel Syndrome Unfamiliar foods, and stress can exacerbate IBS symptoms, which may include abdominal pain and bloating.3a    Lactobacillus rhamnosus GG may reduce the frequency and severity of abdominal pain in children,4 while probiotic strains like Bifidobacterium lactis and Lactobacillus casei Shirota may help regulate bowel movements and improve stool consistency.5 How Multi-Strain Probiotics Can Help Alleviate Discomfort During Travel Consider adding a multi-strain probiotic supplement to your travel itinerary, such as ProbiFlora™.  ProbiFlora™ which contains multi-strains of well-studied probiotics proven to rebalance the GUT microflora.6 The ProbiFlora™ range includes ProbiFlora™ Adult Intensive Rescue – 9 Strain7, ProbiFlora™ Adult Classic Bowel Support – 4 Strain8, ProbiFlora™ Adult Everyday Flora Balance – 2 Strain9, ProbiFlora™ Rx Intestinal Flora Care10, ProbiFlora™ Junior Everyday Flora Balance11, ProbiFlora™ Probiotic Infant Drops 3 strain-Regular drops12, and ProbiFlora™ Junior Fit For School Chewable Tablets13. ProbiFlora™ – the PROs in probiotic health – to PROtect you and your family with PROven multi-strain benefits. ProbiFloraTM’s range of products are available from leading pharmacies and retailers nationwide. For more information, visit https://probiflora.co.za/ and join the conversations on Instagram and Facebook.     2023102610320533   References:   Kwoji ID, Aiyegoro OA, Okpeku M, Adeleke MA. Multi-strain probiotics: Synergy among isolates enhances biological activities. Biology (Basel). 2021 Apr 13;10(4):322. doi: 10.3390/biology10040322. PMID: 33924344; PMCID: PMC8070017. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070017/. Last accessed September 2023. City of Hope. The skinny on probiotics and a healthy digestive system. Available from: https://www.cancercenter.com/community/blog/2020/07/the-skinny-on-probiotics. Last accessed September 2023. Saha L. Irritable bowel syndrome: pathogenesis, diagnosis, treatment, and evidence-based medicine. World J Gastroenterol. 2014 Jun 14;20(22):6759-73. doi: 10.3748/wjg.v20.i22.6759. PMID: 24944467; PMCID: PMC4051916. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051916/. Last accessed September 2023. Francavilla, R., et al. (2010). A randomized controlled trial of Lactobacillus GG in children with functional abdominal pain. Pediatrics, 126(6), e. Available from: https://pubmed.ncbi.nlm.nih.gov/21078735/. Last accessed September 2023. Araújo MM, Botelho PB. Probiotics, prebiotics, and synbiotics in chronic constipation: Outstanding aspects to be considered for the current evidence. Front Nutr. 2022 Dec 8;9:935830. doi: 10.3389/fnut.2022.935830. PMID: 36570175; PMCID: PMC9773270. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9773270/. Last accessed September 2023. Adcock Ingram data on file. (strain documents) ProbiFlora™ Adult Intensive Rescue Professional Information, 26 August 2021. ProbiFlora™ Adult Classic Bowel Support Professional Information, 21 June 2022. ProbiFlora™ Adult Everyday Flora Balance Professional Information, 20 October 2020. ProbiFlora™ Rx Intestinal Flora Care Professional Information, 2 December 2021. ProbiFlora™ Junior Everyday Flora Balance Professional Information, 25 August 2021. ProbiFlora™ Probiotic Infant Drops 3 Strain Professional Information, 27 June 2020. ProbiFlora™ Junior Fit for School Professional Information, 29 August 2022.

Bonitas – innovation, life stages and quality care

Pregnancy, your body and your baby – week 12 of your pregnancy

This is now the last week of your first trimester, which is week 1 to 12. Your clothes are probably starting to feel a little tighter than they used to, but the good news is that some of the first-trimester pregnancy symptoms, such as morning sickness and fatigue should be easing up soon. During the first trimester, your baby will have grown from an egg to a fully formed baby (with lots of growing to do) and you’ll have had your first check-up and ultrasound. Your body at week 12 At week 12 you’ll probably notice that your morning sickness may start to subside. This is because the hCG hormone is starting to level off. However, not all moms are this lucky, as some experience nausea in their second trimester as well, or even throughout their whole pregnancy. Stomach pain, cramping and constipation are also pregnancy symptoms you may be experiencing.  Not all women experience constipation, however, it is fairly common thanks to pregnancy hormones. If you experience sharp or severe pain, it’s important to seek medical help as quickly as possible. Things to keep in mind Throughout your pregnancy both your mental and physical wellbeing is important. Many articles on pregnancy neglect to explain the mental challenges that expecting moms can struggle with during this time. Pregnancy hormones, the added stresses of a new life growing inside you and previous or current depression and/or anxiety can mean that you may also struggle with antenatal depression and anxiety. Tell-tale signs of antenatal depression are feeling sad or anxious all the time, and lack of interest in things that used to.  If you do feel that you’re struggling it’s important that you reach out to a health care provider and rely on family and friends for support. Joining a support group of moms, or moms-to-be in a similar position can also help you feel more at ease. Where is your baby at in week 12 Your growing baby is now roughly the size of a lime or a plum. At this point all your baby’s important features, body parts and organs are in place, they just have lots of growing and maturing to do. Your baby’s tiny developing bone marrow is starting to make white blood cells and their muscles and nervous system are maturing.

South African Divorce Support Association

How to care for children during divorce

Parents going through a divorce/separation are mostly always concerned about what it is going to do to the children and how to minimise the impact it will have on them. If you want to minimise the negative impact of your relationship breakup on your children, you must first take care of yourself. When going onto a plane, we are always given some safety instructions at first and one of them, in case of cabin de-pressurisation, is to first put on the oxygen mask yourself and then help the person next to you, because in all logic, if you are wanting to help someone else but you are not getting the oxygen yourself, you will struggle and possibly not even be able to help the person next to you. You will end up being the one needing help. Same goes with a relationship breakup. Such an event brings a lot of emotions. Emotions which you may not have been prepared to deal with. Without taking care of yourself first, you will not be a prepared parent to assist your children. Many parents send their children to therapists at this time of high stress, and it is an avenue that is wise to take when you recognise some symptoms which you don’t know how to handle, but truth is, your children need their parents first and foremost at this critical point in their life. Not a stranger. So in order to properly be there for your children and take care of them during and after the divorce/separation, first you must take care of yourself. Here are some recommended steps, specifics for parents going through a divorce. Divorce & Co-Parenting Coaching Divorce & Co-Parenting Coaching is highly recommended for parents concerned about their children’s well-being at this challenging time in their lives. It will allow you to make sense and process your emotions and receive help to help your children. Divorce Mediation Once you have your “oxygen mask” on, i.e, you are working through your own emotions, engaging into Mediation is the best way forward in finalising the details of your ending relationship while keeping an amicable environment for your children. If you think going to court and fighting a legal dispute is scary, imagine how your children must feel! Parenting Plan Equip yourselves with a good parenting plan. There is only so much that one can think of and manage by themselves. A Parenting Plan will assist you to have an overview of what your children need and how it can fit with your needs, now that you have two households to consider.

Dr Gerald B Kaplan

Protecting Your Young Children’s Teeth

It is possible for children to reach adulthood without ever experiencing tooth decay. But  to ensure this, good oral health should begin in infancy. Parents must provide this care in their  child’s early years. Later, parents will need to instruct, monitor and motivate the children to maintain good oral health habits. Children learn healthy practices from their parents, so parents must be good role models. Attitudes and habits established at  an early age are very important for  good oral health throughout one’s life. A child’s  dental care actually begins before birth. A pregnant woman’s diet provides the nutrients required for good development of the unborn child’s  teeth. After the baby is born, good oral health of the newborn can be achieved by gently wiping their mouths and gums after every feeding, putting only water in their bedtime  bottles, and massaging the gums to comfort the child when  teething. When a child is frequently given a bottle contains liquids with  sugar as a pacifier or sleep times, a baby bottle tooth decay can result. This serious condition can destroy the infant’s teeth. If you must give your baby a bottle bedtime, be sure it contains only water. Brushing should begin as soon as the first tooth erupts. Parents should brush and floss a child’s teeth  daily until the child can be taught to do this alone. Then a child’s brushing and flossing should be supervised and encourage  by  parents. Fluoride is one of the most effective ways of preventing tooth decay in children. Fluoride protection can be obtained from the fluoridated drinking water supply, fluoride tablets or drops, fluoride toothpaste and topical fluoride treatments given at our office. Your child’s particular fluoride needs can be discussed with us. Your child’s first dental visit should occur by the first birthday. Then visit should occur regularly was recommended by the dentist. Sealants can provide excellent protection against tooth decay. These are clearer  shaded liquid plastics that are painted onto chewing surfaces of the children’s permanent back teeth. When combined with brushing with fluoride toothpaste and flossing, sealants offer major protection against tooth decay. As a child grows, you should continually encourage preventive dental care routines, such as brushing and flossing, eating a balanced diet and having regular dental checkups.  Your  child may be fortunate enough to say,  “Cavities? Never had them,never will!”

CRYOSAVE

Stem cell banking gives hope

In the heartening narrative penned by Taryn Vollmer, we are granted a profound insight into the transformative power of stem cell preservation and the invaluable role played by CryoSave. Taryn’s journey, marred by personal loss and health challenges, underscores the significance of stem cell harvesting as a beacon of hope in the face of adversity. Through her poignant account, we are reminded of the critical importance of informed choices and proactive measures in safeguarding the health and well-being of our loved ones. Taryn’s story resonates as a testament to the unwavering commitment of CryoSave to deliver exemplary service and support, transcending boundaries to provide reassurance and solace to families worldwide. Tarryn writes to the CryoSave Family: “I am writing to thank you yet again for your fabulous service. This has been the second time we have stored our stem cells with you and you have made the experience a memorable one. I have always felt passionate about my children saving their stem cells.  I had a boyfriend when I was younger and he was diagnosed with Leukaemia at the age of 26.  His only chance of survival was a bone marrow transplant.  He was half Italian and half Scottish so finding a bone marrow match was always going to be a challenge.   We managed to find a match in Germany however it wasn’t a 100% match.  This created all sorts of complications and unfortunately, he died shortly after the transplant.  This was the first time I learned about stem cells and the benefit of harvesting them.  I always wonder if he would be alive today if he had harvested his own at birth.  A thought that could have so easily have been answered if only our parents were more informed regarding stem cells and harvesting. So naturally, when I fell pregnant with my first child, CryoSave was a no-brainer and the process to harvest and store the stem cells was a breeze.  To cut a long story short, we were recently blessed to have another child via a surrogate.  I was diagnosed with breast cancer 5 years ago and to save my life and avoid metastatic breast cancer, the only option that I had was to get rid of the hormone that spreads my cancer namely estrogen.  This resulted in a full hysterectomy at the age of 36.  I had been blessed to have done a fertility cycle before the operation and had two embryos available for surrogacy.  Only two chances of which the first was successful in March this year.  I was unsure if we could do stem cell harvesting using a surrogate.  Everything surrogate-related is very complicated in South Africa so I expected the same with CryoSave.  To say I was pleasantly surprised is an understatement.  The cryo-save people knew exactly what I was talking about and directed myself and my surrogate through the process.  It was simple and easy and harvesting was a dream.  Once again thank you for your excellent service. I now see stem cell harvesting differently.  It is kind of like an insurance policy except it is one that money can’t buy when you need it.   When people die, the loved ones always ask “If only they left a life insurance policy, things would be so different”. Well, in some of these cases, if stem cells were harvested, maybe these people wouldn’t have even died. Medical technology and research are continually changing and I do not doubt that the use of stem cells will exponentially increase over time.  It is an exciting time for a company like CryoSave.” Taryn Vollmer’s heartfelt narrative resonates with a broad audience, illuminating the transformative potential of stem cell preservation and the unwavering support offered by CryoSave. As we reflect on Taryn’s journey—one marked by resilience, hope, and unwavering determination—we are called to action. Let us seize the opportunity to embrace the promise of tomorrow by exploring the possibilities afforded by stem cell preservation. Together, let us embark on a journey of empowerment and enlightenment, fuelled by the belief that through proactive measures and informed choices, we can safeguard the health and well-being of generations to come. Join us in championing the cause of stem cell preservation, for in doing so, we pave the way for a future defined by healing, hope, and boundless possibilities.

Bonitas – innovation, life stages and quality care

Pregnancy, your body and your baby – week 11 of your pregnancy

You are now almost at the end of trimester one, which is good news as the second trimester is often seen as easier than the first. Both you and your baby will have undergone many changes during these first 11 weeks, and you’ll have gone from a hoping-to-be-mom to an expecting one. Pregnancy has its ups and downs, so it’s important that you look after yourself (and by default your growing baby) at this time. How you’ll be feeling at week 11 At week 11 your baby bump may be beginning to show, but don’t worry if your baby bump isn’t showing yet, as this varies from pregnancy to pregnancy. It’s likely that if this is your first pregnancy and you don’t have multi babies inside you, you won’t start showing as quickly. If your morning sickness if beginning to ease you may notice that you’re feeling hungrier than normal. If this is the case, make sure that you fuel up on healthy snacks that are nutritious to both you and your growing baby. You may find that your cravings are completely different from what you’d normally eat, and your old favourite food is one you that makes you feel queasy. Hormones, senses that are heightened and a need for comfort food are all reasons behind these strange (but normal) pregnancy cravings and aversions. Your baby at week 11 Your baby is now the size of a lime or a fig, and their body is slowly starting to straighten out. At this point, your baby’s hands and feet, as well as their ears, nose and mouth are becoming more developed. Hair follicles are beginning to form, as well as nail beds and their reproductive organs are developing, however, you won’t be able to tell gender via ultrasound just yet.

Parenting Hub

Dealing with Colds and Flu in the Warmer Months

We typically associate colds and flu with chilly weather, envisioning long winter nights snuggled up with a warm blanket and a hot cup of tea, nursing a runny nose or a scratchy throat. However, contrary to popular belief, these illnesses can strike at any time of the year, including the warmer months.1 Cepacol®, the brand known for its sore throat lozenges and hot medication, offers guidance on how to deal with colds and flu in the summer and spring months, ensuring you can continue to enjoy the sunshine even if you are under the weather. Why Colds and Flu Can Still Occur in Warmer Weather While it’s true that the viruses that cause colds and flu thrive in dry, cold conditions,2 scratchy throats, stuffy noses, and fevers can strike at any time of the year,1 even on a beautiful, sunny day. The Importance of Prevention The first step in dealing with colds and flu in warmer months is prevention. Regular hand washing is one of the most effective measures to prevent the spread of germs.3 In the summer months, when people are often on the move, carrying hand sanitiser can be a good substitute when soap and water are not readily available. Maintaining a healthy lifestyle is another key to preventing illness.4a This includes eating a balanced diet high in fruit and vegetables4b, exercising regularly4c, getting adequate sleep4d, taking steps to prevent infections (such as regular hand washing4e and vaccines4f), and minimising stress 4g. How to Treat Colds and Flu If you do catch a cold or the flu during the warmer months, treatment will be similar to what you would do during the winter. Rest5a and hydration5b are crucial, with the latter even more critical in warmer weather when your body may be losing more fluids through sweating. Over-the-counter medications can help alleviate symptoms such as congestion, sore throat, and fever.5c While your instinct may be to stay indoors, if your symptoms are mild and you’re feeling up to it, try to spend some time outside. Fresh air and sunshine can boost your mood and speed up your recovery. Vitamin D, obtained from sunlight, plays an essential role in immune function.6 How the Cepacol® Cough & Cold Range Can Provide Relief With various formulations available, such as lozenges, throat spray, medicated drinks, and syrup, Cepacol® makes it convenient for consumers to find the perfect solution for their needs. The Cepacol® Cough & Cold range includes a variety of products packed with multiple benefits: Cepacol® Cough & Cold Syrup7: Offers targeted relief for a persistent cough, congestion, and sore throat. Formulated with ivy leaf and pelargonium, it provides cough relief while combating cold and flu symptoms with their antibacterial and antiviral properties. The non-drowsy formulation is alcohol-free, making it safe to be taken from the age of six.   Cepacol® Plus Cough & Cold Syrup8: Specifically designed for night-time relief, this syrup addresses two troublesome symptoms: coughing and nasal congestion. It combines ivy leaf, pelargonium, and valerian extract, offering night-time cough relief. Cepacol® Throat Spray9: This throat spray combines ivy leaf, pelargonium, and menthol. It quickly numbs the throat, providing temporary pain and discomfort relief. Cepacol® understands the daily needs of individuals experiencing cold or flu symptoms, which is why they have developed these comprehensive solutions. With their range of products, there’s a Cepacol® option for everyone. So, if you’re dealing with colds and flu in the warmer months, rest assured that Cepacol® has you covered! Cepacol®‘s range of products is available at leading pharmacies and retailers nationwide. For more information, visit www.cepacol.co.za and join the conversation on Facebook.       2023082410307736   References:   Murphy R [Verywell Health]. Are Summer Colds Caused by Different Germs Than Winter Colds? Available from : https://www.verywellhealth.com/summer-cold-winter-cold-7556002. Last accessed August 2023. Horizon Health News. Why do viruses spread more in winter? Cold temps are key. Available from : https://www.horizonhealthnews.com/why-do-viruses-spread-more-in-winter-cold-temps-are-key/. Last accessed August 2023. Centers for Disease Control and Prevention. Show Me the Science – Why Wash Your Hands? Available from : https://www.cdc.gov/handwashing/why-handwashing.html. Last accessed August 2023. Harvard Health Publishing. How to boost your immune system. Available from : https://www.health.harvard.edu/staying-healthy/how-to-boost-your-immune-system. Last accessed August 2023. Hopkins Medicine. The Do’s and Don’ts of Easing Cold Symptoms. Available from : https://www.hopkinsmedicine.org/health/wellness-and-prevention/the-dos-and-donts-of-easing-cold-symptoms. Last accessed August 2023. Aranow C. [National Institutes of Health]. Vitamin D and the immune system. Available from : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166406/. Last accessed August 2023. CEPACOL® Cough and colds syrups approved professional information, February 2022 CEPACOL® Plus cough and cold syrup approved professional information, February 2022 CEPACOL® Throat Spray approved professional information, February 2022

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